ALAS2 antibody

Principal name

ALAS2 antibody

Alternative names for ALAS2 antibody

ALASE, ASB, Delta-ALA synthetase, 5-aminolevulinic acid synthase, Delta-aminolevulinate synthase, 5-aminolevulinate synthase erythroid-specific mitochondrial

SwissProt ID

P08680, P18080, P22557 (Human), P43090, Q3ZC31, Q5R557, Q63147, Q9XT75, Q9YHT4

Gene ID

212 (ALAS2), 64607 (alas2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat), Can (Canine), Chk (Chicken), Ze (Zebrafish), African clawed frog, Xen (Xenopus)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of ALAS2 antibody

5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.

General readings

"The major splice variant of human 5-aminolevulinate synthase-2 contributes significantly to erythroid heme biosynthesis." Cox T.C., Sadlon T.J., Schwarz Q.P., Matthews C.S., Wise P.D., Cox L.L., Bottomley S.S., May B.K. Int. J. Biochem. Cell Biol. 36:281-295(2004)

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ALAS2 antibody

Sample (30 ug of whole cell lysate). A: K562. 7.5% SDS PAGE. TA308176 diluted at 1:500. Rabbit IgG Aff - Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ALAS2 antibody

Transfected 293T; WB Suggested Anti-ALAS2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Transfected 293T; ALAS2 antibody - C-terminal region (AP44612PU-N) in Transfected 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  Acris Antibodies GmbH

ALAS2 antibody

ALAS2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

ALAS2 antibody

ALAS2 monoclonal antibody (M01), clone 6C1. Western Blot analysis of ALAS2 expression in Raw 264.7. Mouse IgG2a 6C1 Purified Hu, Ms E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ALAS2 antibody

ALAS2 monoclonal antibody (M02), clone 4D8. Western Blot analysis of ALAS2 expression in Raw 264.7 ( Cat # L024V1 ). Mouse IgG2a 4D8 Purified Hu, Ms E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ALAS2 antibody

Transfected 293T; WB Suggested Anti-ALAS2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Transfected 293T; ALAS2 antibody - N-terminal region (ARP41658_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

ALAS2 antibody

Transfected 293T; WB Suggested Anti-ALAS2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Transfected 293T; ALAS2 antibody - C-terminal region (ARP41659_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

ALAS2 antibody

Transfected 293T; WB Suggested Anti-ALAS2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Transfected 293T; ALAS2 antibody - C-terminal region (ARP41889_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

ALAS2 antibody

Human Kidney; Rabbit Anti-ALAS2 Antibody. Catalog Number: ARP41891. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; ALAS2 antibody - N-terminal region (ARP41891_T100) in Human Kidney cells using Immunohistochemistry Rabbit Purified Bov, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

ALAS2 antibody

Western Blot: ALAS2 Antibody [NBP1-32826] - (30µg of whole cell lysate) A: A431  B: H1299 C: HeLa S3  D: Hep G2  E: MOLT4  7.5% SDS PAGE GTX104139 diluted at 1:1000 Rabbit IgG Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

ALAS2 antibody

Western Blot: ALAS2 Antibody [NBP1-54697] - This Anti-ALAS2 antibody was used in Western Blot of Transfected 293T tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

ALAS2 antibody

Western Blot: ALAS2 Antibody [NBP1-54726] - This Anti-ALAS2 antibody was used in Western Blot of Transfected 293T tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms WB
50 µg / €440.00
  Novus Biologicals Inc.

ALAS2 antibody

Western Blot: ALAS2 Antibody [NBP1-54727] - This Anti-ALAS2 antibody was used in Western Blot of Transfected 293T tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

ALAS2 antibody

Western Blot: ALAS2 Antibody [NBP1-54728] - This Anti-ALAS2 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 5ug/ml. Rabbit Purified Hu P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ALAS2

ALAS2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ALAS2

ALAS2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ALAS2 Lysate (Non-Denatured)

ALAS2 Lysate (Non-Denatured)  
0.1 mg / €270.00
  Abnova Taiwan Corp.

ALAS2 overexpression lysate

ALAS2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

ALAS2 overexpression lysate

ALAS2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

ALAS2 overexpression lysate

ALAS2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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