Aldolase C / ALDOC antibody

Principal name

Aldolase C / ALDOC antibody

Alternative names for Aldolase C / ALDOC antibody

ALDC, Brain-type aldolase, Fructose-bisphosphate aldolase C

SwissProt ID

P05063 (Mouse), P09117 (Rat), P09972 (Human), P53449 (Chick)

Gene ID

230 (ALDOC), 11676 (Aldoc), 24191

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), African clawed frog, Chk (Chicken), Mam (Mammalia), Por (Porcine), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Aldolase C / ALDOC antibody

Aldolases are glycolytic enzymes that catalyze the reversible aldol cleavage of fructose 1,6-bisphosphate and fructose-1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde 3-phosphate or glyceraldehyde, respectively. Three aldolase isozymes are found in mammals, specifically aldolases A, B, and C, each of which is encoded by a separate gene. Aldolase A is generally considered to be a muscle enzyme. Northern alysis of cultured cells suggests that it is present in both neurons and glia. Aldolase B is considered to be a liver-specific enzyme and it is transcriptiolly activated by sigls from hormones and dietary factors. In the adult, Aldolase C is the brain-specific isozyme, with low but detectable activity in fetal tissues. Aldolase C shares 81% amino acid identity with Aldolase A and 70% identity with Aldolase B. Earlier studies using isozyme-specific antibodies report its location in gray matter astrocytes and cells of the pia mater. In situ hybridization of mouse central nervous system using isozyme-specific probes revealed that Aldolase A and C are expressed in complementary cell types: Aldolase A mR is found in neurons; Aldolase C message is detected in astrocytes, some cells of the pia mater, and Purkinje cella. Aldolase C can in some situations be used as an astrocyte marker. However Purkinje cells of the cerebellum contain high levels of the enzyme, so the enzyme is not totally astrocyte specific.

General readings

Wang CF., et al. (2007) Anim Genet. 38(3):203-10.
Arakaki TL., et al. (2004) Protein Sci. 13(12):3077-84.

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 32 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Aldolase C / ALDOC antibody

  Rabbit Polyclonal Aldolase C Antibody  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-ALDOC rabbit polyclonal antibody. (TA590612) Rabbit IgG Purified Hu E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

  Mouse monoclonal ALDOC Antibody (C-term)(Ascites)  
ALDOC Antibody (C-term)(Cat. #TA324945) western blot analysis in 293,CEM cell line and mouse brain,cerebellum tissue lysates (35ug/lane).This demonstrates the ALDOC antibody detected the ALDOC protein (arrow). Mouse IgG3 859CT9.5.3 Ascites Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

  Mouse monoclonal ALDOC Antibody (C-term)  
ALDOC Antibody (C-term)(Cat. #TA324946) western blot analysis in HL-60,293 cell line and mouse brain,spleen lysates (35ug/lane).This demonstrates the ALDOC antibody detected the ALDOC protein (arrow). Mouse IgG3 859CT9.5.3 Purified Hu, Ms WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

  Mouse Monoclonal Aldolase C Antibody (1A1)  
Western Blot: Aldolase C Antibody (1A1) [TA337097] - Blots of crude rat brain lysates. The 1A1 clone binds strongly and cleanly to a band at about 40 kDa. Mouse IgG1 1A1 Purified Rt F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

  Mouse Monoclonal Aldolase C Antibody (4A9)  
Western Blot: Aldolase C Antibody (4A9) [TA337098] - Blots of crude cow cerebellum homogenate. The 4A9 clone binds strongly and cleanly to a band at about 40 kDa. Mouse IgG1 4A9 Purified Bov, Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

  Rabbit Polyclonal Anti-ALDOC Antibody  
WB Suggested Anti-ALDOC Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

  Rabbit Polyclonal Anti-ALDOC Antibody  
WB Suggested Anti-ALDOC Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC (C-term) antibody

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with ALDOC antibody (C-term) (Cat.#AP12365PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Aldolase C / ALDOC (C-term) antibody

Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with ALDOC antibody AP22780PU-N followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Ig Fraction Hu, Ms E, P, WB
0.2 ml / €470.00
  Acris Antibodies GmbH

Aldolase C / ALDOC (N-term) antibody

ALDOC Antibody (N-term) (Cat. #AP50143PU-N) western blot analysis in WiDr cell line lysates (35 µg/lane).This demonstrates the ALDOC antibody detected the ALDOC protein (arrow). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Aldolase C / ALDOC antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ALDOC Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €230.00
  Assay Biotech

Aldolase C / ALDOC antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ALDOC Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €330.00
  Assay Biotech

Aldolase C / ALDOC antibody

Blots of crude cow cerebellum homogenate blotted with Aldolase C. The Aldolase C monoclonal binds strongly and cleanly to a band at about 40 kDa. Mouse IgG1 Aff - Purified Bov, Hu, Mam, Por, Rt ICC/IF, WB
0.1 ml / €380.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

ALDOC - human gene knockout kit via CRISPR

ALDOC - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ALDOC - human gene knockout kit via CRISPR

ALDOC - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ALDOC - human gene knockout kit via CRISPR

ALDOC - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ALDOC - human gene knockout kit via CRISPR

ALDOC - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aldoc - mouse gene knockout kit via CRISPR

Aldoc - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Aldoc - mouse gene knockout kit via CRISPR

Aldoc - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aldoc - mouse gene knockout kit via CRISPR

Aldoc - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Items 1 to 20 of 32 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn