Aldolase C / ALDOC antibody

Principal name

Aldolase C / ALDOC antibody

Alternative names for Aldolase C / ALDOC antibody

ALDC, Brain-type aldolase, Fructose-bisphosphate aldolase C

SwissProt ID

P05063 (Mouse), P09117 (Rat), P09972 (Human), P53449 (Chick)

Gene ID

230 (ALDOC), 323055 (ywhaba), 11676 (Aldoc)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Rb (Rabbit), Ze (Zebrafish), African clawed frog, Chk (Chicken), Mam (Mammalia), Por (Porcine)

Available hosts

Rabbit, Sheep, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Radioimmunoassay (R)

Background of Aldolase C / ALDOC antibody

Aldolases are glycolytic enzymes that catalyze the reversible aldol cleavage of fructose 1,6-bisphosphate and fructose-1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde 3-phosphate or glyceraldehyde, respectively. Three aldolase isozymes are found in mammals, specifically aldolases A, B, and C, each of which is encoded by a separate gene. Aldolase A is generally considered to be a muscle enzyme. Northern alysis of cultured cells suggests that it is present in both neurons and glia. Aldolase B is considered to be a liver-specific enzyme and it is transcriptiolly activated by sigls from hormones and dietary factors. In the adult, Aldolase C is the brain-specific isozyme, with low but detectable activity in fetal tissues. Aldolase C shares 81% amino acid identity with Aldolase A and 70% identity with Aldolase B. Earlier studies using isozyme-specific antibodies report its location in gray matter astrocytes and cells of the pia mater. In situ hybridization of mouse central nervous system using isozyme-specific probes revealed that Aldolase A and C are expressed in complementary cell types: Aldolase A mR is found in neurons; Aldolase C message is detected in astrocytes, some cells of the pia mater, and Purkinje cella. Aldolase C can in some situations be used as an astrocyte marker. However Purkinje cells of the cerebellum contain high levels of the enzyme, so the enzyme is not totally astrocyte specific.

General readings

Wang CF., et al. (2007) Anim Genet. 38(3):203-10.
Arakaki TL., et al. (2004) Protein Sci. 13(12):3077-84.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Aldolase C / ALDOC antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-ALDOC rabbit polyclonal antibody. (TA590612) Rabbit IgG Purified Hu E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

ALDOC Antibody (C-term)(Cat. #TA324945) western blot analysis in 293,CEM cell line and mouse brain,cerebellum tissue lysates (35ug/lane).This demonstrates the ALDOC antibody detected the ALDOC protein (arrow). Mouse IgG3 859CT9.5.3 Ascites Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

ALDOC Antibody (C-term)(Cat. #TA324946) western blot analysis in HL-60,293 cell line and mouse brain,spleen lysates (35ug/lane).This demonstrates the ALDOC antibody detected the ALDOC protein (arrow). Mouse IgG3 859CT9.5.3 Purified Hu, Ms WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

Western Blot: Aldolase C Antibody (1A1) [TA337097] - Blots of crude rat brain lysates. The 1A1 clone binds strongly and cleanly to a band at about 40 kDa. Mouse IgG1 1A1 Purified Rt F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC antibody

Western Blot: Aldolase C Antibody (4A9) [TA337098] - Blots of crude cow cerebellum homogenate. The 4A9 clone binds strongly and cleanly to a band at about 40 kDa. Mouse IgG1 4A9 Purified Bov, Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC (C-term) antibody

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with ALDOC antibody (C-term) (Cat.#AP12365PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Aldolase C / ALDOC (C-term) antibody

Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with ALDOC antibody AP22780PU-N followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Ig Fraction Hu, Ms E, P, WB
0.2 ml / €470.00
  Acris Antibodies GmbH

Aldolase C / ALDOC (N-term) antibody

ALDOC Antibody (N-term) (Cat. #AP50143PU-N) western blot analysis in WiDr cell line lysates (35 µg/lane).This demonstrates the ALDOC antibody detected the ALDOC protein (arrow). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Aldolase C / ALDOC antibody

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with ALDOC polyclonal antibody ( Cat # PAB2583 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Aldolase C / ALDOC antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ALDOC Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €205.00
  Assay Biotech

Aldolase C / ALDOC antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ALDOC Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €310.00
  Assay Biotech

Aldolase C / ALDOC antibody

Human HepG2; WB Suggested Anti-ALDOC Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate; ALDOC antibody - N-terminal region (ARP48273_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Aldolase C / ALDOC antibody

Human Placenta; WB Suggested Anti-ALDOC Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Placenta; ALDOC antibody - C-terminal region (ARP48274_P050) in Human Placenta cells using Western Blot Rabbit Aff - Purified Bov, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Aldolase C / ALDOC antibody

Blots of crude cow cerebellum homogenate blotted with Aldolase C. The Aldolase C monoclonal binds strongly and cleanly to a band at about 40 kDa. Mouse IgG1 Aff - Purified Bov, Hu, Mam, Por, Rt ICC/IF, WB
0.1 ml / €380.00
  Neuromics Antibodies

Aldolase C / ALDOC antibody

ELISA: Aldolase C Antibody [32910002] - Affinity Purified Rabbit Hu E, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Aldolase C / ALDOC antibody

Immunohistochemistry-Paraffin: Aldolase C2/C3/C4 Antibody [NBP1-90954] - Immunohistochemical staining of human hippocampus shows strong positivity in subsets of glial cells. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Aldolase C / ALDOC antibody

Aldolase C / ALDOC Rabbit Aff - Purified Bov, Chk, Hu, Ms, Rt, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Aldolase C / ALDOC

Aldolase C / ALDOC Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Aldolase C / ALDOC

Aldolase C / ALDOC Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Aldolase C / ALDOC (1-364, His-tag)

Aldolase C / ALDOC Human Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

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