ALOX15 / LOG15 antibody

Principal name

ALOX15 / LOG15 antibody

Alternative names for ALOX15 / LOG15 antibody

15-LOX, Arachidonate 15-lipoxygenase

SwissProt ID

P12530 (Rabit), P16050 (Human)

Gene ID

246 (ALOX15)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Por (Porcine), Rb (Rabbit), Rt (Rat), Mky (Monkey)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of ALOX15 / LOG15 antibody

Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

General readings

McDuffie M, Maybee NA, Keller SR, Stevens BK, Garmey JC, Morris MA, Kropf E, Rival C, Ma K, Carter JD, Tersey SA, Nunemaker CS, Nadler JL.
Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes.
Diabetes. 2008 Jan;57(1):199-208. Epub 2007 Oct 16.
PMID: 17940120

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ALOX15 / LOG15 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-ALOX15 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504250) Mouse IgG2b OTI3G8 Purified Can, Hu, Mky, Rt ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

ALOX15 / LOG15 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ALOX15 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504358) Mouse IgG2b OTI7H6 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ALOX15 / LOG15 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-ALOX15 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504213) Mouse IgG2b OTI2G3 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ALOX15 / LOG15 antibody

TA305627 (0.2ug/ml) staining of nuclear HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ALOX15 / LOG15 antibody

WB Suggested Anti-ALOX15 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human heart Rabbit IgG Purified Can, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ALOX15 / LOG15 antibody

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-ALOX15 mouse monoclonal antibody. (TA504249) Mouse IgG2a OTI8C5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ALOX15 / LOG15 antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 3D8 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

ALOX15 / LOG15 (C-term) antibody

Formalin-fixed and paraffin-embedded human lymph tissue reacted with ALOX15 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ALOX15 / LOG15 antibody

ALOX15 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALOX15 expression in mouse spleen. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

ALOX15 / LOG15 antibody

Immunoperoxidase of monoclonal antibody to ALOX15 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1.5 ug/ml] Mouse IgG2a 3D8 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ALOX15 / LOG15 antibody

ALOX15 monoclonal antibody (M07), clone 1A11. Western Blot analysis of ALOX15 expression in HeLa(Cat # L013V1 ). Mouse IgG2a 1A11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ALOX15 / LOG15 antibody

ALOX15 polyclonal antibody ( Cat # PAB11445 ) ( 0.2 µg/ml ) staining of HeLa nuclear extract ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

ALOX15 / LOG15 antibody

Human Heart; WB Suggested Anti-ALOX15 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human heart; ALOX15 antibody - middle region (ARP56030_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

ALOX15 / LOG15 antibody

Western Blot: ALOX15 Antibody [NBP1-06976]- 0.2µg/ml staining of nuclear HeLa lysate (35µg protein in RIPA buffer). Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

ALOX15 / LOG15 antibody

Immunohistochemistry-Paraffin: 15 Lipoxygenase 1 Antibody [NBP1-90336] - Immunohistochemical staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ALOX15 / LOG15

ALOX15 / LOG15 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ALOX15 / LOG15

ALOX15 / LOG15 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ALOX15 / LOG15

ALOX15 / LOG15 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

ALOX15 (Human) Matched Antibody Pair

ALOX15 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ALOX15 overexpression lysate

ALOX15 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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