ALOX5 / LOG5 antibody

Principal name

ALOX5 / LOG5 antibody

Alternative names for ALOX5 / LOG5 antibody

5-lipoxygenase, 5-LO, Arachidonate 5-lipoxygenase

SwissProt ID

P09917 (Human), P12527 (Rat), P48999 (Mouse)

Gene ID

240 (ALOX5), 25290 (Alox5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Rb (Rabbit), Prim (Primate), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ALOX5 / LOG5 antibody

ALOX5(ARACHIDONATE 5-LIPOXYGENASE),also known as LOG5 or 5-LO(5-LIPOXYGENASE), is an enzyme that in humans is encoded by the ALOX5 gene. ALOX5 is a member of the lipoxygenase family of enzymes which also transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases. The enzyme 5-lipoxygenase catalyzes 2 reactions in the formation of leukotrienes. The ALOX5 gene is mapped to chromosome 10q11.21 based on an alignment of the ALOX5 sequence with the genomic sequence. Human 5-LO contains 3 nuclear localization sequences (NLSs) and a phosphorylation site involved in nuclear localization. Compared with age-matched 5-LO competent mice, the 5-LO knockout mice developed less right heart hypertrophy. Pharmacologic inhibition or ALOX5 gene disruption resulted in a significant decrease of beta-amyloid production and gamma-secretase levels. ALOX5 activity is short-lived, apparently in part because of an intrinsic instability of the enzyme.

  1. Quick-Filters:
  2. Cited (1)
  3. Highly Validated (1)

Items 1 to 20 of 37 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ALOX5 / LOG5 pSer523 antibody

Figure 1. Western blot of rat cortex lysate showing specific immunolabeling of the ~80k doublet of 5-LO phosphorylated at Ser523 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the 5-LO Ser523  antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase. Rabbit IgG Aff - Purified Hu, Prim, Rt WB
0.1 ml / €380.00
  Acris Antibodies GmbH

ALOX5 / LOG5 antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-ALOX5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA807013)(1:150) Mouse IgG2a OTI3F1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ALOX5 / LOG5 antibody

TA302414 (0.3µg/ml) staining of Rat Stomach lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ALOX5 / LOG5 antibody

Western blot of rat cortex lysate showing specific immunolabeling of the ~80k doublet of 5-LO phosphorylated at Ser523 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: λ-Ptase). The blot is identical to the control except that it was incubated in λ-Ptase (1200 units for 30 min) before being exposed to the 5-LO Ser523 antibody. The immunolabeling is completely eliminated by treatment with λ-Ptase. Rabbit IgG Purified Hu, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ALOX5 / LOG5 antibody

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human colon and thyroid cancer tissue. Recommended dilution: 1/50-150 The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue  using ALOX5 antibody at dilution 1/50, on the right is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ALOX5 antibody at dilution 1/50. (Original magnification: x 400) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ALOX5 / LOG5 antibody

Predicted cell location: Cytoplasm . Positive control: Human esophagus and lung cancer tissue.Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using ALOX5 antibody at dilution 1/25, on the right is immunohistochemistry of paraffin-embedded Human lung cancer tissue using ALOX5 antibody at dilution 1/25. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ALOX5 / LOG5 antibody

Western blot analysis of extracts from Jurkat cells, using ALOX5 (Phospho-Ser523) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ALOX5 / LOG5 antibody

Western Blot: 5-Lipoxygenase Antibody [TA336527] - Detection of LOX5 in human peripheral leukocytes using TA336527 at 0.5(Lane 1) and 2.0 ug/ml (Lane 2). Rabbit Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ALOX5 / LOG5 antibody

Western Blot: 5-Lipoxygenase Antibody [TA336528] - Detection of LOX5 in human peripheral leukocytes using TA336528 at 0.5(Lane 1) and 2.0 ug/ml (Lane 2). Rabbit Purified Bov, Hu, Ms, Rb, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ALOX5 / LOG5 antibody

Host: Rabbit; Target Name: ALOX5; Sample Tissue: HepG2 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ALOX5 / LOG5 antibody

Western blot analysis on HuvEc cell lysate using Phospho-ALOX5(Ser523) Antibody Rabbit IgG Purified Hu, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ALOX5 / LOG5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALOX5 (RC217259, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALOX5.(1:2000) Mouse IgG1 OTI2C5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ALOX5 / LOG5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALOX5 (RC217259, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALOX5. Mouse IgG1 OTI2C7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ALOX5 / LOG5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALOX5 (RC217259, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALOX5. Mouse IgG1 OTI2B7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ALOX5 / LOG5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALOX5 (RC217259, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALOX5.(1:500) Mouse IgG1 OTI2D7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ALOX5 / LOG5 pSer523 antibody

Western blot of Rat hippocampal lysate showing phospho-specific immunolabelling of the ~80 kDa doublet of 5-LO phosphorylated at Ser523 Rabbit IgG Purified Hu, Mky, Rt WB
0.1 ml / €510.00
  Acris Antibodies GmbH

ALOX5 / LOG5 antibody

Immunohistochemistry analyzes of ALOX5 antibody (Cat.-No.: AP06493PU-N) in paraffin-embedded human skeletal muscle tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

ALOX5 / LOG5 antibody

Human Colon, Adipocytes: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ALOX5 / LOG5 antibody

ALOX5 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALOX5 expression in mouse spleen. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

ALOX5 / LOG5 antibody

ALOX5 polyclonal antibody ( Cat # PAB7097 ) ( 0.3 µg/ml ) staining of rat stomach lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Items 1 to 20 of 37 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn