ALOX5AP / FLAP antibody

Principal name

ALOX5AP / FLAP antibody

Alternative names for ALOX5AP / FLAP antibody

MK-886-binding protein, Arachidonate 5-lipoxygenase-activating protein

SwissProt ID

P20291 (Rat), P20292 (Human), P30355 (Mouse), P30356 (Pig), Q148F2 (Bovin)

Gene ID

241 (ALOX5AP), 11690 (Alox5ap), 29624

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), Hst (Hamster), Mky (Monkey), Op (Opossum), Por (Porcine), Prim (Primate), Rb (Rabbit), Sh (Sheep), Bear, Bt (Bat), Ms (Mouse), Rt (Rat), L (Lizard)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of ALOX5AP / FLAP antibody

Genetic variations in ALOX5AP may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
Note=Genetic variations in ALOX5AP may be associated with susceptibility to myocardial infarction. Involvement in myocardial infarction is however unclear: according to some authors (PubMed:14770184), a 4-SNP haplotype in ALOX5AP confers risk of myocardial infarction, while according to other (PubMed:17304054) ALOX5AP is not implicated in this condition.
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ALOX5AP / FLAP (98-161) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

ALOX5AP / FLAP (28-40) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Can, Elephant, Eq, Hst, Hu, Mky, Op, Platypus, Por, Prim, Rb, Sh E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ALOX5AP / FLAP antibody

  Goat Polyclonal Antibody against FLAP / ALOX5AP (internal)  
TA302488 (0.1µg/ml) staining of Human U937 cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ALOX5AP / FLAP (C-term) antibody

  Goat Anti-FLAP / ALOX5AP (C Term) Antibody  
ALOX5AP / FLAP Goat Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ALOX5AP / FLAP Control Peptide

ALOX5AP / FLAP Purified
50 µg / €220.00
  Acris Antibodies GmbH

ALOX5AP / FLAP antibody

Western blot using Antigen Immunoaffinity purified FLAP antibody (cat.-No. AP05297PU-N at 5 µg/ml) on Human kidney cell lysate (15 µg/Lane). Secondary antibody: Mouse anti-Rabbit HRP at 1/75k dilution. 
Visualized using Pierce West Femto substrate system. Exposure for 5 minutes Rabbit Aff - Purified Hu WB
0.1 mg / €490.00
  Acris Antibodies GmbH

ALOX5AP / FLAP antibody

Western blot using FLAP antibody (cat.-No. AP05297SU-N at 5 µg/ml) on Human kidney cell lysate (15 µg/Lane). Secondary antibody: Mouse anti-Rabbit HRP at 1/25k dilution. Visualized using Pierce West Femto substrate system. Exposure for 5 minutes Rabbit Purified Hu WB
0.1 mg / €380.00
  Acris Antibodies GmbH

ALOX5AP / FLAP antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ALOX5AP / FLAP (148-161) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bov, Bt, Can, Elephant, Eq, Hu, L, Mky, Ms, Op, Platypus, Prim, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

ALOX5AP / FLAP antibody

ALOX5AP / FLAP Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

ALOX5AP / FLAP antibody

ALOX5AP polyclonal antibody ( Cat # PAB7117 ) ( 0.1 µg/ml ) staining of human U-937 cell lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

ALOX5AP / FLAP antibody

Western blot using ALOX5AP polyclonal antibody on human kidney cell lysate.
Lysate used at 15 µg/lane, antibody used at 5 µg/ml. Rabbit Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CRISPR

Catalog No. Species Donor Vector  

ALOX5AP - human gene knockout kit via CRISPR

ALOX5AP - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ALOX5AP - human gene knockout kit via CRISPR

ALOX5AP - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ALOX5AP - human gene knockout kit via CRISPR

ALOX5AP - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ALOX5AP - human gene knockout kit via CRISPR

ALOX5AP - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Alox5ap - mouse gene knockout kit via CRISPR

Alox5ap - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Alox5ap - mouse gene knockout kit via CRISPR

Alox5ap - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Alox5ap - mouse gene knockout kit via CRISPR

Alox5ap - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Alox5ap - mouse gene knockout kit via CRISPR

Alox5ap - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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