ALS2CR4 / TMEM237 antibody

Principal name

ALS2CR4 / TMEM237 antibody

Alternative names for ALS2CR4 / TMEM237 antibody

Transmembrane protein 237, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein

SwissProt ID

Q3V0J1 (Mouse), Q96Q45 (Human)

Gene ID

65062 (TMEM237)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of ALS2CR4 / TMEM237 antibody

TMEM237 or ALS2CR4 is a component of the transition zone in primary cilia and required for ciliogenesis. Defects in TMEM237 are the cause of Joubert syndrome type 14 (JBTS14). An autosomal recessive disorder characterized by severe mental retardation, hypotonia, breathing abnormalities in infancy, and dysmorphic facial features. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable JBTS14 features include renal disease, abnormal eye movements, and postaxial polydactyly.

General readings

"TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone." Huang L., Szymanska K., Jensen V.L., Janecke A.R., Innes A.M., Davis E.E., Frosk P., Li C., Willer J.R., Chodirker B.N., Greenberg C.R., McLeod D.R., Bernier F.P., Chudley A.E., Muller T., Shboul M., Logan C.V., Loucks C.M. expand/collapse author list Boycott K.M. Am. J. Hum. Genet. 89:713-730(2011)

10 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ALS2CR4 / TMEM237 antibody

Western blot analysis of extracts from Jurkat cells, using ALS2CR4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ALS2CR4 / TMEM237 antibody

WB Suggested Anti-ALS2CR4 Antibody Titration: 0.2-1 ug/ml; Positive Control: HT1080 cell lysate Rabbit Aff - Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

ALS2CR4 / TMEM237 antibody

ALS2CR4 / TMEM237 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

ALS2CR4 / TMEM237 antibody

Western blot analysis of extracts from Jurkat cells, using ALS2CR4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

ALS2CR4 / TMEM237 antibody

Western blot analysis of extracts from Jurkat cells, using ALS2CR4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

ALS2CR4 / TMEM237 antibody

Human HT1080; WB Suggested Anti-ALS2CR4 Antibody Titration: 0.2-1 ug/ml. Positive Control: HT1080 cell lysate; ALS2CR4 antibody - middle region (ARP44963_P050) in Human HT1080 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ALS2CR4 / TMEM237 antibody

ALS2CR4 / TMEM237 Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

ALS2CR4 / TMEM237 antibody

ALS2CR4 / TMEM237 Rabbit IgG Aff - Purified Hu, Ms E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

TMEM237 overexpression lysate

TMEM237 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TMEM237 overexpression lysate

TMEM237 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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