Alsin / ALS2 antibody

Principal name

Alsin / ALS2 antibody

Alternative names for Alsin / ALS2 antibody

ALS2CR6, KIAA1563, Amyotrophic lateral sclerosis protein 2, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein

SwissProt ID

P0C5Y8 (Rat), Q920R0 (Mouse), Q96Q42 (Human)

Gene ID

57679 (ALS2), 363235 (Als2)

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Can (Canine), Ms (Mouse), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of Alsin / ALS2 antibody

Defects in ALS2, or Alsin, are the cause of amyotrophic lateral sclerosis 2 (ALS2), juvenile primary lateral sclerosis (JPLS), and infantile-onset ascending spastic paralysis (IAHSP). ALS2 is a neurodegenerative disorder which is closely related to but clinically distinct from juvenile primary lateral sclerosis. It is a progressive paralytic disorder which results from dysfunction of the motor systems comprising the upper motor neurons of the motor cortex and lower motor neurons of the brain stem and spinal cord. JPLS is a neurodegenerative disorder which is closely related to but clinically distinct from amyotrophic lateral sclerosis. It is a progressive paralytic disorder which results from dysfunction of the upper motor neurons of the motor cortex while the lower neurons are unaffected. IAHSP is characterized by progressive spasticity and weakness of limbs.

General readings

Yang Y, Hentati A, Deng HX, Dabbagh O, Sasaki T, Hirano M, Hung WY, Ouahchi K, Yan J, Azim AC, Cole N, Gascon G, Yagmour A, Ben-Hamida M, Pericak-Vance M, Hentati F, Siddique T.
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis.
Nat Genet. 2001 Oct;29(2):160-5.
PMID: 11586297

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Alsin / ALS2 (C-term) antibody

TA305806 (3.8ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Bov, Can, Hu, Ms, Rt P
0.1 mg / €325.00
  OriGene Technologies, Inc.

Alsin / ALS2 antibody

Predicted cell location: Cytoplasm. Positive control: Human liver cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using ALS2 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Alsin / ALS2 antibody

WB Suggested Anti-ALS2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Alsin / ALS2 (1644-1657) antibody

Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bov, Bt, Can, Chk, Elephant, Eq, Hu, Mky, Ms, Platypus, Prim, Rb, Rt, Tr, Xen E, P
50 µg / €470.00
  Acris Antibodies GmbH

Alsin / ALS2 (C-term) antibody

Western blot analysis of ALS2 antibody (C-term) (AP17102PU-N) in mouse lung tissue lysates (35 µg/lane). ALS2 (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Alsin / ALS2 antibody

Western Blot analysis of ALS2 expression in transfected 293T cell line (H00057679-T01) by ALS2 MaxPab polyclonal antibody.

Lane 1: ALS2 transfected lysate(136.07 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Alsin / ALS2 antibody

Alsin / ALS2 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

Alsin / ALS2 antibody

Western Blot analysis of ALS2 expression in transfected 293T cell line (H00057679-T02) by ALS2 MaxPab polyclonal antibody.

Lane 1: ALS2 transfected lysate(135.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Alsin / ALS2 antibody

Western Blot analysis of ALS2 expression in transfected 293T cell line by ALS2 monoclonal antibody (M01), clone 4F9.

Lane 1: ALS2 transfected lysate(184 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 4F9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Alsin / ALS2 antibody

Alsin / ALS2 Mouse IgG1 4F10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Alsin / ALS2 antibody

Alsin / ALS2 Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

Alsin / ALS2 antibody

Human HepG2; WB Suggested Anti-ALS2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HepG2 cell lysate; ALS2 antibody - middle region (ARP57487_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Alsin / ALS2 (C-term) antibody

Alsin (dilution: 3.8µg/ml) Goat IgG Aff - Purified Hu P
0.1 mg / €400.00
  Neuromics Antibodies

Alsin / ALS2 antibody

Immunohistochemistry: Alsin / ALS2 Antibody [NB100-885]-(3.8µg/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Alsin / ALS2 antibody

Alsin / ALS2 Rabbit Serum Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Alsin / ALS2 antibody

Alsin / ALS2 Rabbit IgG Hu WB
0.1 ml / €340.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Alsin / ALS2

Alsin / ALS2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Alsin / ALS2

Alsin / ALS2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ALS2 293T Cell Transient Overexpression Lysate(Denatured)

ALS2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Alsin / ALS2 Lysate (Non-Denatured)

Alsin / ALS2 Lysate (Non-Denatured)  
0.1 mg / €270.00
  Abnova Taiwan Corp.

20 Item(s)

per page
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