AMBRA1 antibody

Principal name

AMBRA1 antibody

Alternative names for AMBRA1 antibody

KIAA1736, Activating molecule in BECN1-regulated autophagy protein 1

SwissProt ID

Q8BYW8 (Mouse), Q9C0C7 (Human)

Gene ID

55626 (AMBRA1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Immunoprecipitation (IP)

Background of AMBRA1 antibody

Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1. Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay. Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death. Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy. Multiple isoforms of Ambra1 are known to exist.

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19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AMBRA1 antibody

Western Blot: AMBRA1 Antibody [TA336728] - WB analysis of AMBRA1 in mouse liver cell lysate. Rabbit Purified Hu, Ms, Rt C, E, ICC/IF, P, WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

AMBRA1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-AMBRA1 rabbit polyclonal antibody. (TA590501) Rabbit IgG Purified Hu ICC/IF, IP, P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

AMBRA1 (C-term) antibody

Western blot analysis of Ambra1 in 3T3 cell lysate with Ambra1 antibody at 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AMBRA1 (N-term) antibody

Western blot analysis of Ambra1 in rat brain tissue lysate with Ambra1 antibody at 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AMBRA1 antibody

Predicted cell location: Cytoplasm. Positive control: Human brain and liver cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using AMBRA1 antibody at dilution 1/50, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

AMBRA1 antibody

Predicted cell location: Cytoplasm. Positive control: Human lymphoma tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human lymphoma tissue using AMBRA1 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

AMBRA1 (C-term) antibody

Human Heart (formalin-fixed, paraffin-embedded) stained with AMBRA1 antibody AP22676PU-N at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

AMBRA1 Control Peptide

AMBRA1
50 µg / €160.00
  Acris Antibodies GmbH

AMBRA1 Control Peptide

AMBRA1
50 µg / €160.00
  Acris Antibodies GmbH

AMBRA1 antibody

Activating molecule in BECN1-regulated autophagy protein 1 (Ambra1) antibody Rabbit Serum Ms ICC/IF, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

AMBRA1 antibody

AMBRA1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

AMBRA1 antibody

Immunohistochemistry of AMBRA1 in human brain with AMBRA1 polyclonal antibody ( Cat # PAB13361 ) at 5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

AMBRA1 antibody

Immunohistochemistry of AMBRA1 in human brain with AMBRA1 polyclonal antibody ( Cat # PAB13362 ) at 5 µg/ml. Rabbit Hu, Ms P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

AMBRA1 antibody

Immunohistochemistry: AMBRA1 Antibody [26190002] - Immunohistochemical analysis of AMBRA1 on human cerebral cortex tissue Rabbit Hu, Rt E, IP, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

AMBRA1 antibody

AMBRA1 Rabbit Serum Hu, Ms, Rt C, P, WB
0.15 ml / €400.00
  Novus Biologicals Inc.

AMBRA1 antibody

Western Blot and Immunoprecipitation: AMBRA1 Antibody [NBP1-30460]-Whole cell lysate from HeLa and 293T cells. Rabbit Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

AMBRA1 antibody

Immunohistochemistry-Paraffin: AMBRA1 Antibody [NBP1-76894] - Human brain with Ambra1 antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AMBRA1

AMBRA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

AMBRA1 overexpression lysate

AMBRA1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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