AMD1 antibody

Principal name

AMD1 antibody

Alternative names for AMD1 antibody

AdoMetDC, SAMDC, S-adenosylmethionine decarboxylase proenzyme

SwissProt ID

P17707 (Human), P17708 (Rat), P50243 (Bovin)

Gene ID

262 (AMD1), 22627 (Ywhae)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Rb (Rabbit), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Chicken, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of AMD1 antibody

S-adenosylmethionine decarboxylase (AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC), is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.

General readings

Tolbert W.D., et al. (2001) Biochemistry. 40:9484-9494Xiong H., et al. (1999) J. Biol. Chem. 274:35059-35066

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AMD1 antibody

Predicted cell location: Cytoplasm. Positive control: Human brain and tonsil tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using AMD1 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

AMD1 antibody

Predicted band size: 38kDa. Positive control: PC3 cell, human seminoma and mouse testis tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: PC3 cell lysate Lane2: Human seminoma tissue lysate Lane3: Mouse testis tissue lysate Lysates: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 40 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AMD1 antibody

Predicted cell location: Nucleus,Cytoplasm. Positive control: Human esophagus and lung cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using AMD1 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

AMD1 antibody

Predicted cell location: Nucleus,Cytoplasm. Positive control: Human gastric and ovarian cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using AMD1 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

AMD1 antibody

WB Suggested Anti-AMD1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

AMD1 (C-term) antibody

Immunohistochemical analysis of paraffin-embedded mammary cancer sections, staining SAMDC in cytoplasm, DAB Chromogenic reaction Rabbit IgG Aff - Purified Hu, Ms, Rt C, ICC/IF, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

AMD1 antibody

Western Blot analysis of AMD1 expression in transfected 293T cell line (H00000262-T01) by AMD1 MaxPab polyclonal antibody.

Lane 1: AMD1 transfected lysate(36.74 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

AMD1 antibody

Western blot analysis of rat kidney tissue lysate. Using AMD1 polyclonal antibody ( Cat # PAB8007 ) . Rabbit Hu, Ms, Rb, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

AMD1 antibody

Human THP-1; WB Suggested Anti-AMD1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: THP-1 cell lysate; AMD1 antibody - N-terminal region (ARP54480_P050) in Human THP-1 cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

AMD1 antibody

AMD1 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

AMD1 antibody

Western blot analysis of AMD1 expression in A431 (A); HepG2 (B); SP2/0 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

AMD1 antibody

Western blot analysis of AMD1 expression in A431 (A); HepG2 (B); SP2/0 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

AMD1 antibody

Western blot analysis of AMD1 expression in A431 (A); HepG2 (B); SP2/0 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

AMD1 antibody

AMD1 Rabbit IgG Hu, Ms, Rt C, ICC/IF, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

AMD1 antibody

Immunohistochemistry-Paraffin: AMD1 Antibody [NBP1-87093] Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells of tubules. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

AMD1 antibody

Immunohistochemistry-Paraffin: AMD1 Antibody [NBP1-87094] Immunohistochemical staining of human placenta shows distinct nuclear positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AMD1 (transcript variant 1)

AMD1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

AMD1 (68-334, His-tag)

AMD1 Human Purified > 80 % by SDS - PAGE E. coli
50 µg / €730.00
  Acris Antibodies GmbH

AMD1 (68-334, His-tag)

AMD1 Human Purified > 80 % by SDS - PAGE E. coli
10 µg / €300.00
  Acris Antibodies GmbH

AMD1

AMD1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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