Androgen receptor antibody

Principal name

Androgen receptor antibody

Alternative names for Androgen receptor antibody

Dihydrotestosterone receptor, DHTR, NR3C4, Nuclear receptor subfamily 3 group C member 4

SwissProt ID

P10275 (Human), P15207 (Rat), P19091 (Mouse), Q9GKL7 (Pig), Q9TT90 (Canfa)

Gene ID

367 (AR), 11835 (Ar)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Mky (Monkey), Bov (Bovine), Prim (Primate)

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Dot blot (Dot)

Background of Androgen receptor antibody

The androgen receptor (AR) is an approx. 110 kDa androgen-dependent transcription factor that is a member of the steroid/nuclear receptor gene superfamily. The AR sigling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain. Abnormalities in the AR sigling pathway have been linked to a number of diseases, including prostate cancer, Kennedy's disease and male infertility. The PI3K/Akt sigling pathway plays an important role in regulating AR activity through phosphorylation of AR at Ser213/210 and Ser791/790. Growth factors or cytokines may induce phosphorylation of AR through the PI3K/Akt pathway. IGF-1 activates the phosphatidylinositol 3-kise(PI3K)/AKT pathway in LNCap at high passage number and increases phosphorylation of of AR at Ser213/210 (see western blot) and Ser791/790 (Lin et al. 2003). The western blot results also show that inhibition of the PI3K/Akt pathway by LY294002 prior to incubation with IGF-1 suppressed AR phosphorylation at Ser213/210. Activation of the PI3K/AKt pathway is thought to have a survival role in prostate cancer by protecting cells from apoptosis.

General readings

1. Trapman J, Klaassen P, Kuiper GG, van der Korput JA, Faber PW, van Rooij HC, Geurts van Kessel A, Voorhorst MM, Mulder E, Brinkmann AO. Cloning, structure and expression of a cDNA encoding the human androgen receptor. Biochem Biophys Res Commun. 1988 May 31;153(1):241-8.
PMID: 3377788.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Androgen receptor antibody

Western Blot: Androgen Receptor Antibody (2H8) [TA336773] - Western blot analysis using Androgen Receptor mouse mAb against Androgen Receptor (aa221-321)-hIgGFc transfected HEK293 cell lysate. Mouse IgG1 2H8 Purified Hu C, E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Human Prostate Carcinoma stained with anti-Androgen Receptor (AR) antibody. Rabbit IgG SP107 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Immunohistochemical analysis of paraffin-embedded human human testis (left) and prostate cancer (right) tissues using Androgen Receptor mouse mAb with DAB staining. Mouse IgG1 2H8 Ascites Hu E, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

Androgen receptor antibody

Immunoperoxidase of monoclonal antibody to AR on formalin-fixed paraffin-embedded human renal cell carcinoma tissue. [antibody concentration 3ug/ml] Mouse IgG1 1G3 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Androgen receptor (N-term) antibody

Human prostate carcinoma stained with anti-AR antibody AM20267PU Rabbit IgG SP107 Purified Hu, Ms, Rt P, WB
0.5 ml / €530.00
  Acris Antibodies GmbH

Androgen receptor (N-term) antibody

Human prostate carcinoma stained with anti-AR antibody AM20267PU Rabbit IgG SP107 Purified Hu, Ms, Rt P, WB
1 ml / €760.00
  Acris Antibodies GmbH

Androgen receptor (N-term) antibody

Human prostate carcinoma stained with anti-AR antibody AM20267PU Rabbit IgG SP107 Purified Hu, Ms, Rt P, WB
0.1 ml / €300.00
  Acris Antibodies GmbH

Androgen receptor antibody

Human prostate ca. stained with Anti-AR antibody Rabbit Purified Hu, Ms, Rt ICC/IF, IP, P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

Androgen receptor antibody

Human prostate ca. stained with Anti-AR antibody Rabbit Purified Hu, Ms, Rt ICC/IF, IP, P, WB
1 ml / €530.00
  Acris Antibodies GmbH

Androgen receptor antibody

Human prostate ca. stained with Anti-AR antibody Rabbit Purified Hu, Ms, Rt P, WB
0.1 ml / €200.00
  Acris Antibodies GmbH

Androgen receptor (N-term) antibody

TA302952(0.3µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Immunofluorescence analysis of HeLa cells, using Androgen Receptor (Phospho-Ser94) antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma, using Androgen Receptor (Ab-213) Antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Western blot analysis of extracts from LOVO cells, using Androgen Receptor (Ab-650) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Western blot analysis of Androgen Receptor expression in LOVO whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Western blot analysis of extracts from Jurkat cells, treated with UV (15mins), using Androgen Receptor (Phospho-Tyr363) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Western blot analysis of extracts from K562 cells, treated with EGF (200ng/ml, 5mins), using Androgen Receptor (Ab-363) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Western blot analysis of extracts of various cell lines, using AR antibody. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Androgen receptor Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Androgen receptor antibody

Western Blot: Androgen Receptor [p Ser213, p Ser210] Antibody (156C135.2) [TA336428] - LNCaP cells (passage number 38) were serum-starved for 2 days.  After serum starvation, cells were (A) left untreated, (B) treated with 100 ng/ml IGF-1 for 4h, or & Mouse IgG1 156C135.2 Purified Hu, Prim C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

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