Angiogenin antibody

Principal name

Angiogenin antibody

Alternative names for Angiogenin antibody

ANG, RNASE5, Ribonuclease 5

SwissProt ID

P03950 (Human), P21570 (Mouse), P27043 (Chick), P31346 (Pig)

Gene ID

283 (ANG), 11727 (Ang)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Angiogenin antibody

Angiogenin is a member of the ribonuclease superfamily with approximately 35% amino acid sequence identity with pancreatic RNase. Like other members of the ribonuclease superfamily, angiogenin is a cytotoxic agent that can eliminate cellular protein synthesis. Angiogenin causes inhibition of protein synthesis by functioning as a cytotoxic tRNA-specific RNase. Angiogenesis is the formation of blood vessels or capillaries from existing blood vessels due to specific signals. Angiogenin induces the growth of new blood vessels. It stimulates capillary and umbilical vein endothelial cells to produce diacylglycerol and secrete prostacyclin by phospholipase activation. Angiogenin exhibits both angiogenic and non-angiogenic activities and is involved in endothelial cell migration, proliferation, and differentiation. It is produced by a variety of tumor and normal cell types. Cells that express angiogenin include vascular endothelial and smooth muscle cells, fibroblasts, normal colonic epithelium, normal peripheral blood lymphocytes, lung and colonic epithelial tumor cell lines, and primary gastrointestinal adenocarcinomas. Angiogenin is also present in normal human plasma.

General readings

Moroianu J and Riordan JF. Identification of the nucleolar targeting signal of human angiogenin. Biochem. Biophys. Res. Commun. 1994; 203:1765-72.
Hu G, Riordan JF, and Vallee BL. Angiogenin promotes invasiveness of cultured endothelial cells by stimulation of cell-associated proteolytic activities. Proc. Natl. Acad. Sci. USA 1994; 91:12096-100.
Pyatibratov MG and Kostyukova AS. New insights into the role of angiogenin in actin polymerization. Int. Rev. Cell. Mol. Biol. 2012; 295:175-98.
Li S, Ibaragi S, and Hu GF. Angiogenin as a molecular target for the treatment of prostate cancer. Curr. Cancer Ther. Rev. 2011; 7:83-90.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Angiogenin (Center) antibody

  Rabbit Polyclonal ANG Antibody  
Western blot analysis of ANG in rat liver tissue lysate with Ang antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Angiogenin antibody

  Rabbit Polyclonal Anti-ANG Antibody  
Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Human normal liver tissue, Human fetal liver tissue, Primary antibody: (ANG Antibody) at dilution 1/133, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Angiogenin antibody

BM4113 Angiogenin antibody staining of Human Placenta Frozen Section. Mouse IgM MANG1 Supernatant Hu C, E, P
0.15 mg / €460.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ANG - human gene knockout kit via CRISPR

ANG - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ANG - human gene knockout kit via CRISPR

ANG - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ANG - human gene knockout kit via CRISPR

ANG - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ANG - human gene knockout kit via CRISPR

ANG - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ang - mouse gene knockout kit via CRISPR

Ang - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ang - mouse gene knockout kit via CRISPR

Ang - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ang - mouse gene knockout kit via CRISPR

Ang - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ang - mouse gene knockout kit via CRISPR

Ang - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Angiogenin (transcript variant 1)

  Recombinant protein of human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 1  
Angiogenin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Angiogenin (transcript variant 2)

  Recombinant protein of human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 2  
Angiogenin Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

Angiogenin (25-147, His-tag)

Angiogenin Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Angiogenin (25-147, His-tag)

Angiogenin Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

ELISA Kits

Catalog No.    

OmniKine™ Human Angiogenin ELISA Kit

OmniKine™ Human Angiogenin ELISA Kit  
96 Tests / €440.00
  Assay Biotech

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ANG (mGFP-tagged) - Human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ANG (mGFP-tagged) - Human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, ANG (mGFP-tagged) - Human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ANG (mGFP-tagged) - Human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, ANG (Myc-DDK tagged) - Human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ANG (Myc-DDK tagged) - Human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, ANG (Myc-DDK tagged) - Human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ANG (Myc-DDK tagged) - Human angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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