Angiopoietin-4 antibody

Principal name

Angiopoietin-4 antibody

Alternative names for Angiopoietin-4 antibody

ANG-4, ANG4, ANG-3, ANG3, ANGPT4

SwissProt ID

Q24K15 (Bovin), Q9WVH6 (Mouse), Q9Y264 (Human)

Gene ID

51378 (ANGPT4), 11602 (Angpt4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Angiopoietin-4 antibody

Mouse Angiopoietin3 (ANG3), is a secreted glycoprotein belonging to the angiopoietin family. It has the characteristic structural motifs of angiopoietins including the coiled coiled domain near the amino-terminus and a fibrinogen like domain at the C-terminus. Mouse ANG 3 cDNA encodes a 509 amino acid (aa) precursor protein with a 21 aa signal peptide. It shares 47%, 46% and 54% aa sequence identity with mouse ANG1, mouse ANG2 and human ANG4, respectively. Although the sequence homology is much higher between the human and mouse counterparts for ANG1 (97%) and ANG2 (85%), mouse ANG3 is believed to be an ortholog of human ANG4 based on chromosomal localization studies. Human ANG4 is highly expressed in lung and in cultured human umbilical vein endothelial cells (HUVECs). In contrast, mouse ANG3 is expressed in multiple mouse tissues. Human ANG4 is an agonist that can bind and activate Tie2, a receptor tyrosine kinase with immunoglobulin and epidermal growth factor homology domains expressed primarily on endothelial cells and early hematopoietic cells. Mouse ANG3 has been reported to be a Tie2 antagonist. It is likely that mouse ANG3, like ANG2, may exert agonist or antagonist activities depending on the cell context.

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Angiopoietin-4 antibody

  Rabbit Polyclonal Anti-ANGPT4 Antibody - N-terminal region  
WB Suggested Anti-ANGPT4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Angiopoietin-4 antibody

  Rabbit Polyclonal Anti-ANGPT4 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Human right lung tissue, Human left lung cancer tissue, Primary antibody: (ANGPT4 Antibody) at dilution 1/480, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Angiopoietin-4 antibody

Angiopoietin-4 Rat IgG2 2H34 Purified Ms WB
0.1 mg / €440.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Angpt4 - mouse gene knockout kit via CRISPR

Angpt4 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Angpt4 - mouse gene knockout kit via CRISPR

Angpt4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Angpt4 - mouse gene knockout kit via CRISPR

Angpt4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Angpt4 - mouse gene knockout kit via CRISPR

Angpt4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ANGPT4 overexpression lysate

ANGPT4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ANGPT4 (mGFP-tagged) - Human angiopoietin 4 (ANGPT4), 200 uL, >10^7 TU/mL

Lenti ORF particles, ANGPT4 (mGFP-tagged) - Human angiopoietin 4 (ANGPT4), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ANGPT4 (Myc-DDK tagged) - Human angiopoietin 4 (ANGPT4) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ANGPT4 (Myc-DDK tagged) - Human angiopoietin 4 (ANGPT4) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Angpt4 (GFP-tagged) - Mouse angiopoietin 4 (Angpt4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Angpt4 (GFP-tagged) - Mouse angiopoietin 4 (Angpt4), 200 uL, >10^7 TU/mL  
200 µl / €1,130.00
  OriGene Technologies, Inc.

Lenti ORF particles, Angpt4 (Myc-DDK-tagged) - Mouse angiopoietin 4 (Angpt4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Angpt4 (Myc-DDK-tagged) - Mouse angiopoietin 4 (Angpt4), 200 uL, >10^7 TU/mL  
200 µl / €1,010.00
  OriGene Technologies, Inc.

12 Item(s)

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