ANGPTL4 / FIAF antibody

Principal name

ANGPTL4 / FIAF antibody

Alternative names for ANGPTL4 / FIAF antibody

Angiopoietin-related protein 4, Angiopoietin-like 4, ARP4, HFARP, PGAR, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein

SwissProt ID

Q2KJ51 (Bovin), Q2TNK5 (Pig), Q6TMA8 (Rat), Q9BY76 (Human), Q9Z1P8 (Mouse)

Gene ID

51129 (ANGPTL4), 57875 (Angptl4), 362850

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ANGPTL4 / FIAF antibody

Angiopoietin-related protein 4 (ANGPTL4), also known as angiopoietin-like protein 4, hepatic fibrinogengiopoietin-related protein, ARP4, HFARP, PGAR, NL2, FIAF, pp1158, and ANGPTL2, stops proliferation, movement, and tubule formation of endothelial cells and helps to prevent vascular leaking. ANGPTL4 is critical for regulation of glucose homeostasis and insulin sensitivity. The ANGPTL4 protein is a hormone that controls lipid metabolism and helps to regulate apoptosis. ANGPTL4 is characterized by hypoxia-induced expression in endothelial cells. During periods of hypoxia, ANGPTL4 is found in high levels in the sub-endothelial extracellular matrix, and the increased presence of ANGPTL4 hinders the adhesion of the endothelial cells. Many researchers believe ANGPTL4 can inhibit tumor motility and invasiveness as well as regulate angiogenesis. ANGPTL4 is a member of the angiopoietingiopoientin-like gene family and is found in high levels in the placenta, heart, liver, muscle, pancreas, and lungs. Lower levels of ANGPTL4 can be found in the brain and kidney. Researchers have found that increasing levels of ANGPTL4 in patients with breast cancer can prevent further cancer movement and growth as ANGPTL4 stops the tumor's ability to adhere (PMID: 21860410). Other researchers, however, believe higher levels of ANGPTL4 actually help colorectal cancer metastasize (PMID: 21937683). A third group of research indicates that screening for ANGPTL4 could help determine the origin of clear-cell carcinomas (PMID: 20454689).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ANGPTL4 / FIAF antibody

  Rabbit anti-ANGPTL4 Polyclonal Antibody  
Western blot analysis of extracts of mouse skeletal muscle, using ANGPTL4 antibody. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF antibody

  Rabbit polyclonal anti-Angptl4 (FIAF) antibody  
Western blot analysis of FIAF expression in rat adipose tissue extract. Rabbit Aff - Purified Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF antibody

  Anti-ANGPTL4 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human cervical and esophagus cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using ANGPTL4 antibody at dilution 1/25, on the right is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ANGPTL4 antibody at dilution 1/25. (Original magnification: x100) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF antibody

  Anti-ANGPTL4 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100.The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ANGPTL4 antibody at dilution 1/25. (Original magnification: ×100) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF antibody

  Rabbit Polyclonal Angiopoietin-like Protein 4/ANGPTL4 Antibody  
Western Blot: ANGPTL4 Antibody [TA336910] - WB analysis of ANGPTL4 in 1) Human pancreas 2) Human lung 3) Human lymph node 4) Human adipose and 5) Human breast cancer lysate. Rabbit Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF (Center) antibody

Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ANGPTL4 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Angptl4 - mouse gene knockout kit via CRISPR

Angptl4 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Angptl4 - mouse gene knockout kit via CRISPR

Angptl4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Angptl4 - mouse gene knockout kit via CRISPR

Angptl4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Angptl4 - mouse gene knockout kit via CRISPR

Angptl4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

ELISA Kits

Catalog No.    

Human ANGPTL4 ELISA Kit

Human ANGPTL4 ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ANGPTL4 overexpression lysate

ANGPTL4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

ANGPTL4 overexpression lysate

ANGPTL4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ANGPTL4 (mGFP-tagged) - Human angiopoietin-like 4 (ANGPTL4), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ANGPTL4 (mGFP-tagged) - Human angiopoietin-like 4 (ANGPTL4), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ANGPTL4 (mGFP-tagged)-Human angiopoietin-like 4 (ANGPTL4), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, ANGPTL4 (mGFP-tagged)-Human angiopoietin-like 4 (ANGPTL4), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, ANGPTL4 (Myc-DDK tagged) - Human angiopoietin-like 4 (ANGPTL4), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ANGPTL4 (Myc-DDK tagged) - Human angiopoietin-like 4 (ANGPTL4), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, ANGPTL4 (Myc-DDK-tagged)-Human angiopoietin-like 4 (ANGPTL4), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, ANGPTL4 (Myc-DDK-tagged)-Human angiopoietin-like 4 (ANGPTL4), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €840.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Angptl4 (GFP-tagged) - Mouse angiopoietin-like 4 (Angptl4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Angptl4 (GFP-tagged) - Mouse angiopoietin-like 4 (Angptl4), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Angptl4 (Myc-DDK-tagged) - Mouse angiopoietin-like 4 (Angptl4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Angptl4 (Myc-DDK-tagged) - Mouse angiopoietin-like 4 (Angptl4), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Angptl4 (GFP-tagged ORF) - Rat angiopoietin-like 4 (Angptl4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Angptl4 (GFP-tagged ORF) - Rat angiopoietin-like 4 (Angptl4), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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