ANGPTL4 / FIAF antibody

Principal name

ANGPTL4 / FIAF antibody

Alternative names for ANGPTL4 / FIAF antibody

Angiopoietin-related protein 4, Angiopoietin-like 4, ARP4, HFARP, PGAR, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein

SwissProt ID

Q2KJ51 (Bovin), Q2TNK5 (Pig), Q6TMA8 (Rat), Q9BY76 (Human), Q9Z1P8 (Mouse)

Gene ID

51129 (ANGPTL4), 57875 (Angptl4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of ANGPTL4 / FIAF antibody

Angiopoietin-related protein 4 (ANGPTL4), also known as angiopoietin-like protein 4, hepatic fibrinogengiopoietin-related protein, ARP4, HFARP, PGAR, NL2, FIAF, pp1158, and ANGPTL2, stops proliferation, movement, and tubule formation of endothelial cells and helps to prevent vascular leaking. ANGPTL4 is critical for regulation of glucose homeostasis and insulin sensitivity. The ANGPTL4 protein is a hormone that controls lipid metabolism and helps to regulate apoptosis. ANGPTL4 is characterized by hypoxia-induced expression in endothelial cells. During periods of hypoxia, ANGPTL4 is found in high levels in the sub-endothelial extracellular matrix, and the increased presence of ANGPTL4 hinders the adhesion of the endothelial cells. Many researchers believe ANGPTL4 can inhibit tumor motility and invasiveness as well as regulate angiogenesis. ANGPTL4 is a member of the angiopoietingiopoientin-like gene family and is found in high levels in the placenta, heart, liver, muscle, pancreas, and lungs. Lower levels of ANGPTL4 can be found in the brain and kidney. Researchers have found that increasing levels of ANGPTL4 in patients with breast cancer can prevent further cancer movement and growth as ANGPTL4 stops the tumor's ability to adhere (PMID: 21860410). Other researchers, however, believe higher levels of ANGPTL4 actually help colorectal cancer metastasize (PMID: 21937683). A third group of research indicates that screening for ANGPTL4 could help determine the origin of clear-cell carcinomas (PMID: 20454689).

General readings

General / background references:Kersten S et al. Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J Biol Chem 275:28488-93 (2000). PubMed PMID: 10862772

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ANGPTL4 / FIAF antibody

Western blot analysis of extracts of mouse skeletal muscle, using ANGPTL4 antibody. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF antibody

Western Blot analysis of ANGPTL4 expression in transfected 293T cell line (H00051129-T02) by ANGPTL4 MaxPab polyclonal antibody.

Lane 1: ANGPTL4 transfected lysate(44.66 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu, Ms, Rt E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

Western blot analysis of FIAF expression in rat adipose tissue extract. Rabbit Aff - Purified Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF antibody

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human cervical and esophagus cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using ANGPTL4 antibody at dilution 1/25, on the right is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ANGPTL4 antibody at dilution 1/25. (Original magnification: x100) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF antibody

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100.The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ANGPTL4 antibody at dilution 1/25. (Original magnification: ×100) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF antibody

Western Blot: ANGPTL4 Antibody [TA336910] - WB analysis of ANGPTL4 in 1) Human pancreas 2) Human lung 3) Human lymph node 4) Human adipose and 5) Human breast cancer lysate. Rabbit Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF antibody

ELISA: ANGPTL4 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

ANGPTL4 / FIAF Control Peptide

ANGPTL4 / FIAF
50 µg / €190.00
  Acris Antibodies GmbH

ANGPTL4 / FIAF (Center) antibody

Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ANGPTL4 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ANGPTL4 / FIAF antibody

ANGPTL4 / FIAF Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

ANGPTL4 MaxPab rabbit polyclonal antibody. Western Blot analysis of ANGPTL4 expression in mouse liver. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

ANGPTL4 / FIAF Mouse IgG 1F7 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

ANGPTL4 / FIAF Mouse IgG1 1A12 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

ANGPTL4 / FIAF Mouse IgG2b 1F19 Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

Western blot analysis of Human ANGPTL4 (Angiopoietin-Like 4) polyclonal antibody ( Cat # PAB0007 ) . Rabbit Hu WB
50 µg / €390.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

Western blot analysis of Mouse ANGPTL4 (Angiopoietin-Like 4) polyclonal antibody ( Cat # PAB0008 ) . Rabbit Ms WB
50 µg / €390.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

ANGPTL4 / FIAF Rabbit Ms E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

Western blot analysis of Angptl4 expression in rat adipose tissue extract. Rabbit Ms, Rt WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

ANGPTL4 / FIAF antibody

ANGPTL4 / FIAF Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

ANGPTL4 / FIAF antibody

Western blot analysis of ANGPTL4 expression in A549 (A); 293T (B); U87MG (C); SGC (D) whole cell lysates. Rabbit Aff - Purified Hu WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

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