ANKK1 antibody

Principal name

ANKK1 antibody

Alternative names for ANKK1 antibody

PKK2, SGK288, Ankyrin repeat and protein kinase domain-containing protein 1, Protein kinase PKK2, X-kinase, Sugen kinase 288

SwissProt ID

Q8BZ25 (Mouse), Q8NFD2 (Human)

Gene ID

255239 (ANKK1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of ANKK1 antibody

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ANKK1 (ankyrin repeat and kinase domain containing 1), also known as PKK2 or SGK288, is a 765 amino acid protein that belongs to the Ser/Thr protein kinase family and contains 12 ANK repeats and one protein kinase domain. Highly expressed in brain tissue and present in lower amounts in placenta and spinal cord, ANKK1 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play a role in alcohol and nicotine dependence. The gene encoding ANKK1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.

General readings

Dick DM, Wang JC, Plunkett J, Aliev F, Hinrichs A, Bertelsen S, Budde JP, Goldstein EL, Kaplan D, Edenberg HJ, Nurnberger J Jr, Hesselbrock V, Schuckit M, Kuperman S, Tischfield J, Porjesz B, Begleiter H, Bierut LJ, Goate A.
Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.
Alcohol Clin Exp Res. 2007 Oct;31(10):1645-53.
PMID: 17850642

10 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ANKK1 antibody

TA305881 (0.1ug/ml) staining of Human Substantia Nigra lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ANKK1 antibody

Western blot analysis of extracts from HeLa cells, using ANKK1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ANKK1 antibody

ANKK1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

ANKK1 antibody

Western blot analysis of extracts from HeLa cells, using ANKK1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

ANKK1 antibody

Western blot analysis of extracts from HeLa cells, using ANKK1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

ANKK1 antibody

Western Blot: ANKK1 Antibody[NBP1-28459]- (0.1ug/ml) staining of Human Substantia Nigra lysate (35ug protein in RIPA buffer). Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

ANKK1 antibody

ANKK1 Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

ANKK1 antibody

ANKK1 Rabbit IgG Aff - Purified Hu E, WB
50 µg / €290.00
  Novus Biologicals Inc.

ANKK1 antibody

Immunohistochemistry-Paraffin: ANKK1 Antibody [NBP1-86849] - Immunohistochemistry-Paraffin: ANKK1 Antibody [NBP1-86849] Immunohistochemical staining of human testis shows cytoplasmic positivity in cells in seminiferus ducts and leydig cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

ANKK1 overexpression lysate

ANKK1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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