ANKLE2 / KIAA0692 antibody

Principal name

ANKLE2 / KIAA0692 antibody

Alternative names for ANKLE2 / KIAA0692 antibody

Ankyrin repeat and LEM domain-containing protein 2

SwissProt ID

Q6P1H6 (Mouse), Q7TP65 (Rat), Q86XL3 (Human)

Gene ID

23141 (ANKLE2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Chicken

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of ANKLE2 / KIAA0692 antibody

ANKLE2 or KIAA0692 is a single-pass membrane protein. It contains 1 ANK repeat and 1 LEM domain. It contains 1 RING-type zinc finger. It is involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. ANKLE2 coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex.

General readings

"Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis." Asencio C., Davidson I.F., Santarella-Mellwig R., Ly-Hartig T.B., Mall M., Wallenfang M.R., Mattaj I.W., Gorjanacz M. Cell 150:122-135(2012)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ANKLE2 / KIAA0692 (Center) antibody

Western blot analysis of ANKLE2 in SW480 cell lysate with ANKLE2 antibody at (A) 1 and (B) 2 ug/mL. Chicken Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ANKLE2 / KIAA0692 antibody

WB Suggested Anti-KIAA0692 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: 293T cell lysateThere is BioGPS gene expression data showing that ANKLE2 is expressed in HEK293T Rabbit Aff - Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

ANKLE2 / KIAA0692 (Center) Control Peptide

ANKLE2 / KIAA0692
50 µg / €160.00
  Acris Antibodies GmbH

ANKLE2 / KIAA0692 antibody

Human 293T; WB Suggested Anti-KIAA0692 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 293T cell lysate. There is BioGPS gene expression data showing that ANKLE2 is expressed in HEK293T.; KIAA0692 antibody - middle region (ARP55170_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ANKLE2 / KIAA0692 antibody

Western Blot: ANKLE2 Antibody [NBP1-70407] - This Anti-KIAA0692 antibody was used in Western Blot of 293T tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

ANKLE2 / KIAA0692 antibody

Immunohistochemistry-Paraffin: ANKLE2 Antibody [NBP1-82970] - Immunohistochemical staining of human testis shows cytoplasmic and nuclear positivity in cells in seminiferus ducts. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

ANKLE2 overexpression lysate

ANKLE2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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