Ankyrin-2 antibody

Principal name

Ankyrin-2 antibody

Alternative names for Ankyrin-2 antibody

Brain ankyrin, Ankyrin-B, ANK2, Non-erythroid ankyrin

SwissProt ID

Q01484 (Human), Q8C8R3 (Mouse)

Gene ID

287 (ANK2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Ankyrin-2 antibody

Members of the Ankyrin family of proteins mediate the attachment of integral membrane proteins to the cytoskeleton. ANK1, ANK2 and ANK3 genes encode for the proteins in this family, Ankyrin-1 (also designated Ankyrin R), Ankyrin B and Ankyrin G, respectively. The proteins are structured similarly each composed of an N-terminal domain with multiple ankyrin repeats, a highly conserved central spectrin binding domain, and C-terminal regulatory domains which are susceptible to the most variance. Both Ankyrin B and Ankyrin G are essential for normal neuronal functions. Ankyrin B, or brain Ankyrin is predominantly expressed in the plasma membrane of neurons as well as glial cells throughout the brain. Two transcripts have been described with alternative splicing resulting in additional isoforms. The Ankyrin B protein associates with the spectrin-actin network, mediates axon fasciculation, and stabilizes axon bundles. Ankyrin B is required for coordinated assembly of Na/Ca exchanger, Na/K ATPase, and inositol trisphosphate (InsP(3)) receptor at transverse-tubule/sarcoplasmic reticulum sites in cardiomyocytes.

  1. Quick-Filters:
  2. Highly Validated (2)

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Ankyrin-2 antibody

Adult rat brain membrane immunoblot Mouse IgG2a N105/17 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Ankyrin-2 antibody

Adult rat brain membrane immunoblot Mouse IgG2a N105/17 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Ankyrin-2 antibody

Western blot analysis of Ankyrin-B in rat brain membrane tissues, using a 1:1000 dilution of the antibody Mouse IgG1 S105-13 Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ankyrin-2 antibody

Western blot of rat brain membrane lysates showing the detection of ~200kDa Ankyrin B protein using Anti-Ankryin B antibody [S105-17] (TA326444).? Lane 1: MW ladder. Lane 2: Anti-Ankyrin? B (1:1000). Lane 3: Negative control (no primary Ab). Load: 33 µ pe Mouse IgG2a S105-17 Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ankyrin-2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N105/13 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Ankyrin-2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N105/13 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Ankyrin-2 (transcript variant 2)

Ankyrin-2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

7 Item(s)

per page
  • LinkedIn