Annexin A5 / ANXA5 antibody

Principal name

Annexin A5 / ANXA5 antibody

Alternative names for Annexin A5 / ANXA5 antibody

Annexin-5, Annexin V, Lipocortin V, Endonexin II, Calphobindin I, Anchorin CII, ANX5, ENX2, PP4, CBP-I, PAP-I, VAC-alpha, Placental anticoagulant protein I, Placental anticoagulant protein 4, Thromboplastin inhibitor, Vascular anticoagulant-alpha

SwissProt ID

P08758 (Human), P14668 (Rat), P17153 (Chick), P48036 (Mouse), P81287 (Bovin)

Gene ID

308 (ANXA5), 11747 (Anxa5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit), African clawed frog, Ze (Zebrafish), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine), Sh (Sheep)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), ELISA (detection) (E(detection)), Frozen Sections (C), EPair for Elisa (EPair)

Background of Annexin A5 / ANXA5 antibody

Annexins are a family of calcium-dependent phospholipid-binding proteins. All annexins have been shown to have putative binding site for protein kinases C but only annexin V would possess a potential pseudo-substrate site. Thus annexin V seems to modulate the activity of some PKCs on their substrates. Annexin V was found to play a major role in matrix vesicle-initiated cartilage calcification as a collage-regulated calcium channel. Annexin V?s preferential binding partner is phosphatidylserine (PS). PS is predominantly located in membrane leaflets, which face the cytosol. However, recent findings show that each cell type has the molecular machinery to expose PS at its cell surface. This machinery is activated during the execution of apoptosis. Once PS is exposed at the cell surface it exhibits procoagulant and proinflammatory activities. Annexin V will bind to the PS-exposing apoptotic cell and can inhibit the procoagulant and proinflammatory activities of the dying cell. These findings together with the presence of Annexin V in the extracellular space depict a novel pathophysiological significance for Annexin V in vivo. The occurrence of autoantibodies to annexin V has been described in several pathological disorders. It is concluded that extracellular annexin V provides an antigenic stimulus for autoantibody production. Such autoantibodies may have a detrimental role interfering with putative functions of annexin V.

General readings

Jeong JJ., et al. (2014) J. Biol. Chem. 289 (4), 2469-2481Liu BC., et al. (2013) Am. J. Physiol. Renal Physiol. 305 (3), F304-F313

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Annexin A5 / ANXA5 antibody

Western blot analysis of Annexin V expression in Jurkat cell lysate Rabbit Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Annexin A5 / ANXA5 antibody

Western blot analysis of extracts of extracts of HeLa cell lines, using ANXA5 antibody. Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Annexin A5 / ANXA5 antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1F4-1A5 Purified Hu E, ICC/IF, IP, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Annexin A5 / ANXA5 antibody

Immunofluorescence of purified MaxPab antibody to ANXA5 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Annexin A5 / ANXA5 antibody

ANXA5 MaxPab rabbit polyclonal antibody. Western Blot analysis of ANXA5 expression in mouse liver. Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Annexin A5 / ANXA5 antibody

ANXA5 MaxPab rabbit polyclonal antibody. Western Blot analysis of ANXA5 expression in mouse liver. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Annexin A5 / ANXA5 antibody

Immunoperoxidase of monoclonal antibody to ANXA5 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] Mouse IgG1 1F4-1A5 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Annexin A5 / ANXA5 antibody

Predicted band size: 36 kDa . Positive control: Mouse eyes and heart, Human cervical cancer tissue, OP9 and RAW264.7 cell lysate. Recommended dilution: 1/500-2000 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Annexin A5 / ANXA5 antibody

Predicted band size: 36 kDa . Positive control: Human cervical cancer tissue lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lysate: 40 ug Primary antibody: 1/750 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Annexin A5 / ANXA5 antibody

WB Suggested Anti-ANXA5 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Annexin A5 / ANXA5 antibody

WB Suggested Anti-ANXA5 Antibody Titration: 0.625 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Annexin A5 / ANXA5 antibody

Immunofluorescent staining of HeLa cells using anti-ANXA5 rabbit polyclonal antibody (TA590069). Rabbit IgG Purified Can, Hu, Mky, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Annexin A5 / ANXA5 antibody

Annexin A5 / ANXA5 Mouse IgG2a VAA-33 Biotin Hu F
100 Tests / €420.00
  Acris Antibodies GmbH

Annexin A5 / ANXA5 antibody

Annexin A5 / ANXA5 Mouse IgG2a VAA-33 FITC Hu F
100 Tests / €440.00
  Acris Antibodies GmbH

Annexin A5 / ANXA5 antibody

Annexin A5 / ANXA5 Mouse IgG2a VAA-33 Purified Hu E, F
0.1 mg / €400.00
  Acris Antibodies GmbH

Annexin A5 / ANXA5 antibody

Immunofluorescence staining of a 7 days old zebrafish embryo. Mouse IgG1 RUU-WAC2A Purified Hu, Ze C, F, ICC/IF, P
0.1 mg / €320.00
  Acris Antibodies GmbH

Annexin A5 / ANXA5 (C-term) antibody

Western blot analysis of Annexin V antibody (C-term) (AP17111PU-N) in SK-Br-3 cell line lysates (35 µg/lane). Annexin V (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Annexin A5 / ANXA5 (C-term) antibody

Immunohistochemical analysis of paraffin embedded rat tissue sections (cardiac muscle) usin Annexin V antibody Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Annexin A5 / ANXA5 antibody

Annexin A5 / ANXA5 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Annexin A5 / ANXA5 antibody

Annexin A5 / ANXA5 Mouse IgG2a VAA-33 Hu E, F, WB
0.1 mg / €730.00
  Abnova Taiwan Corp.

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