Anoctamin-5 / ANO5 antibody

Principal name

Anoctamin-5 / ANO5 antibody

Alternative names for Anoctamin-5 / ANO5 antibody

GDD1, TMEM16E, Gnathodiaphyseal dysplasia 1 protein, Transmembrane protein 16E

Gene ID

203859 (ANO5)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Anoctamin-5 / ANO5 antibody

ANO5 is a member of the anoctamin family of transmembrane proteins. This protein is likely a calcium activated chloride channel.
Defects in ANO5 are the cause of gnathodiaphyseal dysplasia (GDD), also known as osteogenesis imperfecta with unusual skeletal lesions or gnathodiaphyseal sclerosis. GDD is a rare skeletal syndrome characterized by bone fragility, sclerosis of tubular bones, and cemento-osseous lesions of the jawbone. Patients experience frequent bone fractures caused by trivial accidents in childhood; however the fractures heal normally without bone deformity. The jaw lesions replace the tooth-bearing segments of the maxilla and mandible with fibrous connective tissues, including various amounts of cementum-like calcified mass, sometimes causing facial deformities. Patients also have a propensity for jaw infection and often suffer from purulent osteomyelitis-like symptoms, such as swelling of and pus discharge from the gums, mobility of the teeth, insufficient healing after tooth extraction and exposure of the lesions into the oral cavity.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Anoctamin-5 / ANO5 (C-term) antibody

Western blot analysis of AP21362PU-N ANO5 Antibody (C-term) in Mouse spleen tissue lysates (35 µg/lane). ANO5 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Anoctamin-5 / ANO5 antibody

Anoctamin-5 / ANO5 Rabbit Serum Hu, Ms C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Anoctamin-5 / ANO5 antibody

Anoctamin-5 / ANO5 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

3 Item(s)

per page
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