AOC2 / RAO antibody

Principal name

AOC2 / RAO antibody

Alternative names for AOC2 / RAO antibody

Amine oxidase copper-containing, Retina-specific copper amine oxidase

SwissProt ID

O75106 (Human), Q812C9 (Mouse)

Gene ID

314 (AOC2), 237940 (Aoc2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Chk (Chicken), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of AOC2 / RAO antibody

Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.

General readings

"Adipogenesis-related increase of semicarbazide-sensitive amine oxidase and monoamine oxidase in human adipocytes." Bour S., Daviaud D., Gres S., Lefort C., Prevot D., Zorzano A., Wabitsch M., Saulnier-Blache J.-S., Valet P., Carpene C. Biochimie 89:916-925(2007)
"The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase." Kaitaniemi S., Elovaara H., Groen K., Kidron H., Liukkonen J., Salminen T., Salmi M., Jalkanen S., Elima K. Cell. Mol. Life Sci. 66:2743-2757(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AOC2 / RAO antibody

Human Lung; WB Suggested Anti-AOC2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Lung; AOC2 antibody - middle region (AP43408PU-N) in Human Lung cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Aoc2 - mouse gene knockout kit via CRISPR

Aoc2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Aoc2 - mouse gene knockout kit via CRISPR

Aoc2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aoc2 - mouse gene knockout kit via CRISPR

Aoc2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aoc2 - mouse gene knockout kit via CRISPR

Aoc2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AOC2 / RAO (transcript variant 2)

  Recombinant protein of human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2  
AOC2 / RAO Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

AOC2 overexpression lysate

AOC2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

AOC2 overexpression lysate

AOC2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, AOC2 (mGFP-tagged) - Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, AOC2 (mGFP-tagged) - Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,610.00
  OriGene Technologies, Inc.

Lenti ORF particles, AOC2 (mGFP-tagged) - Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, AOC2 (mGFP-tagged) - Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, AOC2 (Myc-DDK tagged) - Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, AOC2 (Myc-DDK tagged) - Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,450.00
  OriGene Technologies, Inc.

Lenti ORF particles, AOC2 (Myc-DDK tagged) - Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, AOC2 (Myc-DDK tagged) - Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Aoc2 (GFP-tagged) - Mouse amine oxidase, copper containing 2 (retina-specific) (Aoc2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Aoc2 (GFP-tagged) - Mouse amine oxidase, copper containing 2 (retina-specific) (Aoc2), 200 uL, >10^7 TU/mL  
200 µl / €1,460.00
  OriGene Technologies, Inc.

Lenti ORF particles, Aoc2 (Myc-DDK-tagged) - Mouse amine oxidase, copper containing 2 (retina-specific) (Aoc2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Aoc2 (Myc-DDK-tagged) - Mouse amine oxidase, copper containing 2 (retina-specific) (Aoc2), 200 uL, >10^7 TU/mL  
200 µl / €1,310.00
  OriGene Technologies, Inc.

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