AP2 complex subunit mu-1 / AP2M1 antibody

Principal name

AP2 complex subunit mu-1 / AP2M1 antibody

Alternative names for AP2 complex subunit mu-1 / AP2M1 antibody

CLAPM1, KIAA0109, Adaptin-mu2, AP-2 mu-2 chain, Plasma membrane adaptor AP-2 50 kDa protein, HA2 50 kDa subunit, Clathrin assembly protein complex 2 medium chain, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP5

SwissProt ID

P84091 (Mouse), P84092 (Rat), Q3ZC13 (Bovin), Q5ZMP6 (Chick), Q96CW1 (Human)

Gene ID

1173 (AP2M1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Mky (Monkey), Ze (Zebrafish), Can (Canine)

Available hosts

Chicken, Rabbit, Mouse

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of AP2 complex subunit mu-1 / AP2M1 antibody

The AP-2 coat assembly protein complex is an important component of clathrin-coated pits involved in receptor-mediated endocytosis at the plasma membrane. Each AP-2 heterotetramer is composed of a, ß, µ, and s protein subunits. The 50 kDa µ subunit (AP-2µ, AP2M1) is located at the core of the AP-2 complex and mediates interaction between the cargo protein and the clathrin-coated pit. The carboxy-termil AP2M1 region recognizes the tyrosine-based, endocytotic sorting motif YXXf found in cargo proteins and helps to bring the cargo protein to the clathrin-coated pit. Non-canonical, tyrosine-based endocytotic sorting sigls can also promote interaction between cargo proteins and AP2M1. AP2M1 plays an essential role in molecular sigling as it couples receptor-mediated endocytosis and pathways involving membrane receptors, matrix metalloproteises, and ion channel proteins. Phosphorylation of specific AP2M1 residues and binding of lipids to this adaptor protein can regulate AP2M1 activity. Phosphorylation of AP2M1 at Thr156 by adaptor-associated kise 1 (AAK1) stimulates affinity binding of AP2M1 to cargo protein sigls.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AP2 complex subunit mu-1 / AP2M1 antibody

Anti-AP2M1 mouse monoclonal antibody (TA503015) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY AP2M1(RC201377). Mouse IgG2a OTI1F10 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AP2 complex subunit mu-1 / AP2M1 antibody

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-AP2M1 monoclonal antibody. Mouse IgG2a OTI2G2 Purified Hu, Ms F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AP2 complex subunit mu-1 / AP2M1 antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-AP2M1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503019) Mouse IgG2a OTI1E9 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

AP2 complex subunit mu-1 / AP2M1 antibody

Immunofluorescent staining of HeLa cells using anti-AP2M1 mouse monoclonal antibody (TA503020). Mouse IgG2a OTI1B11 Purified Hu, Mky F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AP2 complex subunit mu-1 / AP2M1 antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-AP2M1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503021) Mouse IgG1 OTI 2F11 Purified Can, Hu, Rt F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AP2 complex subunit mu-1 / AP2M1 antibody

Western blot analysis of AP2M1 in human kidney tissue lysate with AP2M1 antibody at (A) 1 and (B) 2 ug/ml. Chicken IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AP2 complex subunit mu-1 / AP2M1 antibody

Sample(30 ug of whole cell lysate). A:293T. B:HeLa S3. 10% SDS PAGE. TA308343 diluted at 1:500 Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AP2 complex subunit mu-1 / AP2M1 antibody

Western blot analysis of extracts of HepG2 cell line, using AP2M1 antibody. Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AP2 complex subunit mu-1 / AP2M1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AP2M1 (RC201377, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AP2M1. Mouse IgG2a OTI1C12 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AP2 complex subunit mu-1 / AP2M1 antibody

Anti-AP2M1 mouse monoclonal antibody (TA503018) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY AP2M1(RC201377). Mouse IgG2a OTI1C8 Purified Can, Hu, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AP2 complex subunit mu-1 / AP2M1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AP2M1 (RC201377, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AP2M1. Mouse IgG2b OTI2D10 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AP2 complex subunit mu-1 / AP2M1 Control Peptide

AP2 complex subunit mu-1 / AP2M1
50 µg / €160.00
  Acris Antibodies GmbH

AP2 complex subunit mu-1 / AP2M1 (C-term) antibody

Western blot analysis in mouse Neuro-2a cell line lysates (35µg/lane) using AP2M1 Antibody (C-term) Cat.-No AP50202PU-N. This demonstrates the AP2M1 antibody detected the AP2M1 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

AP2 complex subunit mu-1 / AP2M1 antibody

Western blot analysis of AP2M1 expression in SKBR3 (A); MCF7 (B); mouse brain (C); rat brain (D) whole cell lysates. Rabbit Aff - Purified Bov, Chk, Hu, Mky, Ms, Rt, Ze WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

AP2 complex subunit mu-1 / AP2M1 antibody

Western blot analysis of AP2M1 expression in SKBR3 (A); MCF7 (B); mouse brain (C); rat brain (D) whole cell lysates. Rabbit Aff - Purified Bov, Chk, Hu, Mky, Ms, Rt, Ze WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

AP2 complex subunit mu-1 / AP2M1 antibody

Western blot analysis of AP2M1 expression in SKBR3 (A); MCF7 (B); mouse brain (C); rat brain (D) whole cell lysates. Rabbit Aff - Purified Bov, Chk, Hu, Mky, Ms, Rt, Ze WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

AP2 complex subunit mu-1 / AP2M1 antibody

Western Blot: AP2M1 Antibody [NBP1-32272]- (30 µg of whole cell lysate) A:293T B:HeLa S3 10% SDS PAGE diluted at 1:500 Rabbit IgG Hu P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

AP2 complex subunit mu-1 / AP2M1 antibody

Western Blot: AP2M1 Antibody (EP2695Y) [NBP1-40491] -  Western blot analysis on (A) MCF-7, (B) SKBR-3 cell lysates using anti-AP2 mu1, dilution 1:1000. Rabbit IgG EP2695Y Hu, Ms, Rt F, ICC/IF, WB
0.1 ml / €480.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AP2 complex subunit mu-1 / AP2M1 (transcript variant 2)

AP2 complex subunit mu-1 / AP2M1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

AP2 complex subunit mu-1 / AP2M1

AP2 complex subunit mu-1 / AP2M1 Human
2 µg / €300.00
  Abnova Taiwan Corp.

Items 1 to 20 of 23 total

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