APBB1 / FE65 antibody

Principal name

APBB1 / FE65 antibody

Alternative names for APBB1 / FE65 antibody

RIR, Amyloid beta A4 precursor protein-binding family B member 1

SwissProt ID

O00213 (Human), P46933 (Rat), Q9QXJ1 (Mouse)

Gene ID

11785 (Apbb1), 322 (APBB1), 29722

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of APBB1 / FE65 antibody

The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known. [provided by RefSeq]. Transcript Variant: This variant (2) differs in the 5' UTR and the coding region (compared to variant 1). This results in a protein that maintains the reading frame but is a shorter isoform (delta E9), compared to isoform E9. This encoded isoform (delta E9) is widely expressed in all non-neuronal cells, but is not expressed in differentiated neurons. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Hoe HS, Magill LA, Guenette S, Fu Z, Vicini S, Rebeck GW. FE65 Interaction with the apoE receptor ApoEr2. J Biol Chem. 2006 Apr 25; [Epub ahead of print] PMID: 16638748

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APBB1 / FE65 antibody

Western blot analysis of extracts of various cell lines, using APBB1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

APBB1 / FE65 antibody

Detection of FE65 protein in HEK 293 cell lysate Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APBB1 / FE65 antibody

TA302412 (0.1µg/ml) staining of NIH/3T3 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APBB1 / FE65 antibody

WB Suggested Anti-Apbb1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Mouse Heart Rabbit IgG Purified Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

APBB1 / FE65 antibody

APBB1 polyclonal antibody (A01), Lot # 060717JCS1 Western Blot analysis of APBB1 expression in 293 ( Cat # L026V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

APBB1 / FE65 antibody

Immunofluorescence of purified MaxPab antibody to APBB1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

APBB1 / FE65 antibody

APBB1 polyclonal antibody ( Cat # PAB7086 ) ( 0.1 µg/ml ) staining of NIH/3T3 lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

APBB1 / FE65 antibody

Western blot analysis of Apbb1 in HEK 293 cell lysate using Apbb1 polyclonal antibody ( Cat # PAB12116 ). Rabbit Hu, Ms, Rt IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

APBB1 / FE65 (N-term) antibody

APBB1 / FE65 Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

APBB1 / FE65 antibody

Western blot analysis using FE65 and HEK 293 cell lysates Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 ml / €380.00
  Neuromics Antibodies

APBB1 / FE65 antibody

Western Blot: APBB1 Antibody [NB100-41392] - NB100-41392 (0.1ug/ml) staining of NIH/3T3 lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

APBB1 / FE65 antibody

APBB1 / FE65 Rabbit Biotin Hu, Ms, Rt IP, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

APBB1 / FE65 antibody

APBB1 / FE65 Rabbit DyLight488 Hu, Ms, Rt IP, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

APBB1 / FE65 antibody

APBB1 / FE65 Rabbit HRP Hu, Ms, Rt IP, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

APBB1 / FE65 antibody

APBB1 / FE65 Rabbit Aff - Purified Hu, Ms, Rt IP, WB
25 µl / €160.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APBB1 / FE65 (transcript variant 1)

APBB1 / FE65 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APBB1 / FE65 (transcript variant 2)

APBB1 / FE65 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APBB1 / FE65

APBB1 / FE65 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

APBB1 / FE65

APBB1 / FE65 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

APBB1 / FE65

APBB1 / FE65 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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