APBB1 / FE65 antibody

Principal name

APBB1 / FE65 antibody

Alternative names for APBB1 / FE65 antibody

RIR, Amyloid beta A4 precursor protein-binding family B member 1

SwissProt ID

O00213 (Human), P46933 (Rat), Q9QXJ1 (Mouse)

Gene ID

322 (APBB1), 29722 (Apbb1), 11785

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of APBB1 / FE65 antibody

Apbb1 is an adapter protein that forms a transcriptiolly active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domaipbb1 plays a central role in the response to D damage by translocating to the nucleus and inducing apoptosis. Apbb1 may act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), recruiting other pro-apoptosis factors such as MAPK8/JNK1. Apbb1 is required for histone H4 acetylation at double-strand breaks (DSBs). Its ability to specifically bind modified histones and chromatin modifying enzymes such as KAT5/TIP60, probably explains its trancription activation activity.Apbb1 functions in association with TSHZ3, SET and HDAC factors as a transcriptiol repressor, that inhibits the expression of CASP4. Apbb1 is associates with chromatin in a region surrounding the CASP4 transcriptiol start site(s).

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 32 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APBB1 / FE65 antibody

Western blot analysis of extracts of various cell lines, using APBB1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

APBB1 / FE65 antibody

Detection of FE65 protein in HEK 293 cell lysate Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APBB1 / FE65 antibody

TA302412 (0.1µg/ml) staining of NIH/3T3 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APBB1 / FE65 antibody

WB Suggested Anti-Apbb1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Mouse Heart Rabbit IgG Purified Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

APBB1 / FE65 antibody

APBB1 polyclonal antibody (A01), Lot # 060717JCS1 Western Blot analysis of APBB1 expression in 293 ( Cat # L026V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

APBB1 / FE65 antibody

Immunofluorescence of purified MaxPab antibody to APBB1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

APBB1 / FE65 antibody

APBB1 polyclonal antibody ( Cat # PAB7086 ) ( 0.1 µg/ml ) staining of NIH/3T3 lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

APBB1 / FE65 antibody

Western blot analysis of Apbb1 in HEK 293 cell lysate using Apbb1 polyclonal antibody ( Cat # PAB12116 ). Rabbit Hu, Ms, Rt IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

APBB1 / FE65 (N-term) antibody

APBB1 / FE65 Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

APBB1 / FE65 antibody

Western blot analysis using FE65 and HEK 293 cell lysates Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 ml / €380.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

APBB1 - human gene knockout kit via CRISPR

  APBB1 - human gene knockout kit via CRISPR  
APBB1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

APBB1 - human gene knockout kit via CRISPR

  APBB1 - human gene knockout kit via CRISPR  
APBB1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APBB1 / FE65 (transcript variant 1)

APBB1 / FE65 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APBB1 / FE65 (transcript variant 2)

APBB1 / FE65 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APBB1 / FE65

APBB1 / FE65 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

APBB1 / FE65

APBB1 / FE65 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

APBB1 / FE65

APBB1 / FE65 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

APBB1 / FE65

APBB1 / FE65 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

APBB1 / FE65

APBB1 / FE65 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

APBB1 / FE65

APBB1 / FE65 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Items 1 to 20 of 32 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn