APC / DP2.5 antibody

Principal name

APC / DP2.5 antibody

Alternative names for APC / DP2.5 antibody

Adenomatous polyposis coli protein, Deleted in polyposis 2.5

SwissProt ID

P25054 (Human), P70478 (Rat), Q61315 (Mouse)

Gene ID

324 (APC)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Por (Porcine), Bov (Bovine), Chk (Chicken)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of APC / DP2.5 antibody

APC7 (anaphase-promoting complex subunit 7) is a member of the E3 enzyme family. This protein contains TPR repeats and has a molecular weight of approximately 63 kD. The APC7 protein is located in the nucleus during interphase and the centrosome during metaphase/anaphase. This protein probably recruits Cdh1 into the APC complex. The APC7 protein functions with other members of the APC complex as a multisubunit cell cycle ubiquitin ligase, and a regulator of sister chromatid separation by degrading securins. In addition, this protein functions in ubiquitin-dependent cyclin catabolism, metaphase/anaphase transition, and spindle elongation. The APC7 protein comprises one subunit of the anaphase promoting complex including APC1-8, and other probable complex proteins APC9-11, Cdc26, Mnd2, Swm1. The APC complex is inactivated by protein kinase A and is activated by CDC20 and Cdh1.

General readings

1. Dong B  et al. Mammalian diaphanous-related formin 1 regulates GSK3ß-dependent microtubule dynamics required for T cell migratory polarization. PLoS One 8:e80500 (2013). Mouse .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APC / DP2.5 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-APC mouse monoclonal antibody. (TA803655; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 OTI2B8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC / DP2.5 antibody

Human colon carcinoma stained with Anti-APC antibody Rabbit Purified Hu, Ms, Rt P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

APC / DP2.5 antibody

Human colon carcinoma stained with Anti-APC antibody Rabbit Purified Hu, Ms, Rt P, WB
1 ml / €450.00
  Acris Antibodies GmbH

APC / DP2.5 antibody

Human colon carcinoma stained with Anti-APC antibody Rabbit Purified Hu, Ms, Rt P, WB
0.1 ml / €180.00
  Acris Antibodies GmbH

APC / DP2.5 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using APC antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

APC / DP2.5 antibody

Western blot analysis of extracts from HUVEC cells, treated with PMA (125ng/ml, 30mins), using APC (Phospho-Ser2054) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APC / DP2.5 antibody

Western blot analysis of extracts from J COLO205tcells, using APC antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APC / DP2.5 antibody

Western blot analysis on HuvEc cell lysate using APC Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APC / DP2.5 antibody

Western blot analysis on HuvEc cell lysate using Phospho-APC(Ser2054) Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APC / DP2.5 antibody

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (APC Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

APC / DP2.5 antibody

Hela nuclear extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with anti-APC7 antibody (clone Poly6113). Proteins were visualized using a donkey anti-rabbit-IgG secondary conjugated to HRP and chemiluminescence detection. Rabbit Poly6113 Purified Hu WB
50 µl / €248.00
  OriGene Technologies, Inc.

APC / DP2.5 antibody

Human Colon Carcinoma stained with anti-Adenomatous Polyposis Coli (APC) antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

APC / DP2.5 antibody

ELISA: APC Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

APC / DP2.5 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-APC mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803682) Mouse IgG1 OTI1B12 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC / DP2.5 antibody

Figure 1. Mouse APC Rat IgG2a KT44 Aff - Purified Ms E, ICC/IF, WB
1 mg / €910.00
  Acris Antibodies GmbH

APC / DP2.5 antibody

Figure 1. Mouse APC Rat IgG2a KT44 Aff - Purified Ms E, ICC/IF, WB
0.2 mg / €450.00
  Acris Antibodies GmbH

APC / DP2.5 antibody

Figure 1. Mouse APC Rat IgG2a KT44 Aff - Purified Ms E, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

APC / DP2.5 antibody

Figure 1. Mouse APC Rat IgG2a KT45 Aff - Purified Ms E, ICC/IF, WB
1 mg / €910.00
  Acris Antibodies GmbH

APC / DP2.5 antibody

Figure 1. Mouse APC Rat IgG2a KT45 Aff - Purified Ms E, ICC/IF, WB
0.2 mg / €450.00
  Acris Antibodies GmbH

APC / DP2.5 antibody

Figure 1. Mouse APC Rat IgG2a KT45 Aff - Purified Ms E, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

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