APC11 / ANAPC11 antibody

Principal name

APC11 / ANAPC11 antibody

Alternative names for APC11 / ANAPC11 antibody

Anaphase-promoting complex subunit 11, HSPC214, Cyclosome subunit 11, Hepatocellular carcinoma-associated RING finger protein

SwissProt ID

Q3ZCF6 (Bovin), Q9CPX9 (Mouse), Q9NYG5 (Human)

Gene ID

51529 (ANAPC11), 66156 (Anapc11)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of APC11 / ANAPC11 antibody

APC11 is also known as Anaphase promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, and HSPC214. APC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex. APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2. APC11 shows both a cytoplasmic and nuclear localization. APC11 is expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte. APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APC11 / ANAPC11 antibody

  ANAPC11 mouse monoclonal antibody, clone OTI1F2 (formerly 1F2)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506321) Mouse IgG1 OTI1F2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC11 / ANAPC11 antibody

  ANAPC11 (Apc11) mouse monoclonal antibody, clone OTI3F5 (formerly 3F5)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506323) Mouse IgG1 OTI3F5 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

APC11 / ANAPC11 (Center) antibody

  Rabbit Polyclonal APC11 Antibody  
Western blot analysis of APC11 in 3T3 cell tissue lysate with APC11 antibody at (A) 1 and (B) 2 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APC11 / ANAPC11 antibody

  Goat Anti-ANAPC11 Antibody  
TA326323 (1µg/ml) staining of Cerebral Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APC11 / ANAPC11 antibody

  ANAPC11 (Apc11) mouse monoclonal antibody, clone OTI1A8 (formerly 1A8)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506235) Mouse IgG1 OTI1A8 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC11 / ANAPC11 antibody

  ANAPC11 (Apc11) mouse monoclonal antibody, clone OTI1B5 (formerly 1B5)  
Anti-ANAPC11 mouse monoclonal antibody (TA506300) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ANAPC11(RC200097). Mouse IgG2a OTI1B5 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC11 / ANAPC11 antibody

  ANAPC11 (Apc11) mouse monoclonal antibody, clone OTI3C4 (formerly 3C4)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506325) Mouse IgG1 OTI3C4 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC11 / ANAPC11 antibody

  ANAPC11 (Apc11) mouse monoclonal antibody, clone OTI1B11 (formerly 1B11)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ANAPC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506326) Mouse IgG1 OTI1B11 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC11 / ANAPC11 antibody

Figure 1. Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a; amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thiolesters (S) with the mdifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein) /CBC(cullin-2/elongin B/elongin C)-like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked headto-tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. Data contributed by S.Jentsch, see reference 3. Rabbit Serum Hu E, IP, WB
0.1 ml / €450.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Anapc11 - mouse gene knockout kit via CRISPR

Anapc11 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Anapc11 - mouse gene knockout kit via CRISPR

Anapc11 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Anapc11 - mouse gene knockout kit via CRISPR

Anapc11 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Anapc11 - mouse gene knockout kit via CRISPR

Anapc11 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APC11 / ANAPC11 (transcript variant 1)

  Recombinant protein of human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 1  
APC11 / ANAPC11 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

APC11 / ANAPC11 (full length, N-term HIS tag, transcript variant 2)

  Purified recombinant protein of Human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
APC11 / ANAPC11 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ANAPC11 overexpression lysate

ANAPC11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

ANAPC11 overexpression lysate

ANAPC11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

ANAPC11 overexpression lysate

ANAPC11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

ANAPC11 overexpression lysate

ANAPC11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

ANAPC11 overexpression lysate

ANAPC11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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