APC2 / ANAPC2 antibody

Principal name

APC2 / ANAPC2 antibody

Alternative names for APC2 / ANAPC2 antibody

Anaphase-promoting complex subunit 2, KIAA1406, Cyclosome subunit 2

SwissProt ID

Q8BZQ7 (Mouse), Q9UJX6 (Human)

Gene ID

29882 (ANAPC2)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of APC2 / ANAPC2 antibody

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Attard,T.M., (2008) Dis. Colon Rectum 51 (2), 207-212

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  2. Highly Validated (2)

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APC2 / ANAPC2 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ANAPC2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503411) Mouse IgG2a OTI1A6 Purified Hu, Mky, Ms, Rt F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

APC2 / ANAPC2 antibody

Anti-ANAPC2 mouse monoclonal antibody (TA503407) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ANAPC2(RC207539). Mouse IgG1 OTI1H8 Purified Hu, Ms, Rt F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC2 / ANAPC2 antibody

Anti-ANAPC2 mouse monoclonal antibody (TA503404) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ANAPC2(RC207539). Mouse IgG1 OTI1B12 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC2 / ANAPC2 antibody

Anti-ANAPC2 mouse monoclonal antibody (TA503405) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ANAPC2(RC207539). Mouse IgG1 OTI2A1 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC2 / ANAPC2 antibody

Anti-ANAPC2 mouse monoclonal antibody (TA503406) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ANAPC2(RC207539). Mouse IgG1 OTI1B11 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC2 / ANAPC2 antibody

Anti-ANAPC2 mouse monoclonal antibody (TA503573) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ANAPC2(RC207539). Mouse IgG2a OTI3E1 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APC2 / ANAPC2 (C-term) antibody

Formalin-Fixed Paraffin-Embedded Human Skin stained with APC2 Antibody Cat.-No AP07544SU-N at 1/500 dilution after heat-induced antigen retrieval. Rabbit Serum Hu E, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

APC2 / ANAPC2 antibody

Figure 1. Conjugation pathways for ubiquitin and
ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a; amino acid).
Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thiolesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein)/CBC(cullin-2/elongin
B/elongin C)-like E3 enzymes that are also involved in ubiquitination.
In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked headto-
tail. Whether HUB1 functions as a modifier is currently unclear.
APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. Data contributed by S. Jentsch, see ref. 3. Rabbit Serum Hu E, IP, WB
0.1 ml / €440.00
  Acris Antibodies GmbH

APC2 / ANAPC2 antibody

ANAPC2 MaxPab polyclonal antibody. Western Blot analysis of ANAPC2 expression in human liver. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

APC2 / ANAPC2 antibody

APC2 / ANAPC2 Mouse IgG1 8G2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

APC2 / ANAPC2 antibody

APC2 / ANAPC2 Mouse IgG1 7F2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

APC2 / ANAPC2 antibody

Human Skin; Skin; APC2 antibody - middle region (ARP50526_P050) in Human Skin cells using Immunohistochemistry Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APC2 / ANAPC2

APC2 / ANAPC2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

APC2 / ANAPC2

APC2 / ANAPC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

APC2 / ANAPC2

APC2 / ANAPC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ANAPC2 overexpression lysate

ANAPC2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

APC2 / ANAPC2 Lysate(Denatured)

APC2 / ANAPC2 Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

17 Item(s)

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