APC2 antibody

Principal name

APC2 antibody

Alternative names for APC2 antibody

APCL, APC-like, Adenomatous polyposis coli protein 2, Adenomatous polyposis coli protein-like

SwissProt ID

O95996 (Human), Q9Z1K7 (Mouse)

Gene ID

10297 (APC2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of APC2 antibody

APC2 Antibody: Cell cycle regulated protein ubiquitition and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC2 is a highly conserved component of the aphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading aphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mR and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. Like APC11, APC2 contains cullin and RING finger domains that are thought to be important in regulating ubiquitition activity.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APC2 antibody

  Rabbit Polyclonal APC2 Antibody  
Western blot analysis of APC2 in HeLa cell lysate with APC2 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APC2 antibody

  Rabbit Polyclonal Anti-APC2 Antibody  
WB Suggested Anti-APC2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

APC2 antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

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