APC4 / ANAPC4 antibody

Principal name

APC4 / ANAPC4 antibody

Alternative names for APC4 / ANAPC4 antibody

Anaphase-promoting complex subunit 4, Cyclosome subunit 4

SwissProt ID

Q91W96 (Mouse), Q9UJX5 (Human)

Gene ID

29945 (ANAPC4), 52206 (Anapc4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of APC4 / ANAPC4 antibody

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC4 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC4, it is thought that APC4 associates with other APC/C components APC1, APC5, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APC4 / ANAPC4 antibody

  Rabbit Polyclonal APC4 Antibody  
Western blot analysis of APC4 in mouse liver tissue lysate with APC4 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APC4 / ANAPC4 antibody

  Rabbit Polyclonal Anti-ANAPC4 Antibody  
APC4 / ANAPC4 Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APC4 / ANAPC4 (N-term) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

APC4 / ANAPC4 antibody

APC4 / ANAPC4 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

APC4 / ANAPC4 antibody

Immunofluorescence of purified MaxPab antibody to ANAPC4 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

APC4 / ANAPC4 antibody

Western Blot analysis of ANAPC4 expression in transfected 293T cell line (H00029945-T02) by ANAPC4 MaxPab polyclonal antibody.

Lane 1: ANAPC4 transfected lysate(92.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CRISPR

Catalog No. Species Donor Vector  

Anapc4 - mouse gene knockout kit via CRISPR

Anapc4 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Anapc4 - mouse gene knockout kit via CRISPR

Anapc4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Anapc4 - mouse gene knockout kit via CRISPR

Anapc4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Anapc4 - mouse gene knockout kit via CRISPR

Anapc4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APC4 / ANAPC4

APC4 / ANAPC4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

APC4 / ANAPC4

APC4 / ANAPC4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ANAPC4 293T Cell Transient Overexpression Lysate(Denatured)

ANAPC4 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Anapc4 (GFP-tagged) - Mouse anaphase promoting complex subunit 4 (Anapc4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Anapc4 (GFP-tagged) - Mouse anaphase promoting complex subunit 4 (Anapc4), 200 uL, >10^7 TU/mL  
200 µl / €1,520.00
  OriGene Technologies, Inc.

Lenti ORF particles, Anapc4 (Myc-DDK-tagged) - Mouse anaphase promoting complex subunit 4 (Anapc4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Anapc4 (Myc-DDK-tagged) - Mouse anaphase promoting complex subunit 4 (Anapc4), 200 uL, >10^7 TU/mL  
200 µl / €1,370.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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