APC4 / ANAPC4 antibody

Principal name

APC4 / ANAPC4 antibody

Alternative names for APC4 / ANAPC4 antibody

Anaphase-promoting complex subunit 4, Cyclosome subunit 4

SwissProt ID

Q91W96 (Mouse), Q9UJX5 (Human)

Gene ID

29945 (ANAPC4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C)

Background of APC4 / ANAPC4 antibody

APC4 Antibody: Cell cycle regulated protein ubiquitition and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC4 is a highly conserved component of the aphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading aphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mR and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC4, it is thought that APC4 associates with other APC/C components APC1, APC5, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APC4 / ANAPC4 antibody

Western blot analysis of APC4 in mouse liver tissue lysate with APC4 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APC4 / ANAPC4 (N-term) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

APC4 / ANAPC4 Control Peptide

APC4 / ANAPC4
50 µg / €160.00
  Acris Antibodies GmbH

APC4 / ANAPC4 antibody

APC4 / ANAPC4 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

APC4 / ANAPC4 antibody

Immunofluorescence of purified MaxPab antibody to ANAPC4 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

APC4 / ANAPC4 antibody

Western Blot analysis of ANAPC4 expression in transfected 293T cell line (H00029945-T02) by ANAPC4 MaxPab polyclonal antibody.

Lane 1: ANAPC4 transfected lysate(92.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APC4 / ANAPC4

APC4 / ANAPC4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

APC4 / ANAPC4

APC4 / ANAPC4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ANAPC4 293T Cell Transient Overexpression Lysate(Denatured)

ANAPC4 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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