APC7 / ANAPC7 antibody

Principal name

APC7 / ANAPC7 antibody

Alternative names for APC7 / ANAPC7 antibody

Anaphase-promoting complex subunit 7, Cyclosome subunit 7

SwissProt ID

Q4KMX6 (Human), Q9UJX3 (Human), Q9WVM3 (Mouse)

Gene ID

51434 (ANAPC7)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), African clawed frog, Xen (Xenopus)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of APC7 / ANAPC7 antibody

APC7 (anaphase-promoting complex subunit 7) is a member of the E3 enzyme family. This protein contains TPR repeats and has a molecular weight of approximately 63 kD. The APC7 protein is located in the nucleus during interphase and the centrosome during metaphase/anaphase. This protein probably recruits Cdh1 into the APC complex. The APC7 protein functions with other members of the APC complex as a multisubunit cell cycle ubiquitin ligase, and a regulator of sister chromatid separation by degrading securins. In addition, this protein functions in ubiquitin-dependent cyclin catabolism, metaphase/anaphase transition, and spindle elongation. The APC7 protein comprises one subunit of the anaphase promoting complex including APC1-8, and other probable complex proteins APC9-11, Cdc26, Mnd2, Swm1. The APC complex is inactivated by protein kinase A and is activated by CDC20 and Cdh1. The Poly6113 antibody has been shown to be useful for Western blotting of the human APC7 protein.

General readings

Turnell,A.S., (2005) Nature 438 (7068), 690-695

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APC7 / ANAPC7 antibody

Western blot analysis of APC7 in rat kidney tissue lysate with APC7 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APC7 / ANAPC7 (N-term) antibody

Hela nuclear extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with anti-APC7 antibody (clone Poly6113). Proteins were visualized using a donkey anti-rabbit-IgG secondary conjugated to HRP and chemiluminescence detection. Rabbit IgG Aff - Purified Hu WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

APC7 / ANAPC7 (C-term) antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

APC7 / ANAPC7 Control Peptide

APC7 /  ANAPC7
50 µg / €160.00
  Acris Antibodies GmbH

APC7 / ANAPC7 (N-term) antibody

Hela nuclear extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with anti-APC7 antibody (clone Poly6113). Proteins were visualized using a donkey anti-rabbit-IgG secondary conjugated to HRP and chemiluminescence detection. Rabbit IgG Aff - Purified Hu WB
50 µl / €190.00
  Acris Antibodies GmbH

APC7 / ANAPC7 antibody

Human Intestine; Rabbit Anti-ANAPC7 Antibody. Catalog Number: ARP41605. Paraffin Embedded Tissue: Human Intestine. Cellular Data: Epithelial cells of intestinal villas. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; ANAPC7 antibody - C-terminal region (ARP41605_P050) in Human Intestine cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

APC7 / ANAPC7 antibody

APC7 /  ANAPC7 Rabbit Hu, Ms IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

APC7 / ANAPC7 antibody

Western Blot: Apc7 Antibody [NBP1-58224] - This Anti-ANAPC7 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 0.5ug/ml. Rabbit Aff - Purified Can, Chk, Hu, Ms, Rt, Xen P, WB
50 µg / €440.00
  Novus Biologicals Inc.

APC7 / ANAPC7 antibody

Immunofluorescence: Apc7 Antibody [NBP1-77379] - Rat kidney tissue with APC7 antibody at 20 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APC7 / ANAPC7 (transcript variant 1)

APC7 /  ANAPC7 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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per page
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