APG4C / ATG4C antibody

Principal name

APG4C / ATG4C antibody

Alternative names for APG4C / ATG4C antibody

Autophagin-3, AUTL1, AUTL3, Cysteine protease ATG4C, Autophagy-related protein 4 homolog C, Autophagy-related cysteine endopeptidase 3, AUT-like 3 cysteine endopeptidase

SwissProt ID

Q811C2 (Mouse), Q96DT6 (Human)

Gene ID

84938 (ATG4C)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine)

Available hosts

Sheep, Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Enzyme Immunoassay (E)

Background of APG4C / ATG4C antibody

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.; ENZYME REGULATION: Inhibited by N-ethylmaleimide.; TISSUE SPECIFICITY: Highly expressed in skeletal muscle, heart, liver and testis.;

General readings

"Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy." Marino G., Uria J.A., Puente X.S., Quesada V., Bordallo J., Lopez-Otin C. J. Biol. Chem. 278:3671-3678(2003)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APG4C / ATG4C antibody

Western blot analysis of extracts from K562 cells and COS7 cells, using ATG4C antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APG4C / ATG4C (C-term) antibody

ATG4C antibody (2µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APG4C / ATG4C antibody

WB Suggested Anti-ATG4C Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 721_B cell lysate Rabbit Aff - Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

APG4C / ATG4C antibody

Western blot analysis of ATG4C in A549 cell lysate with ATG4C antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APG4C / ATG4C antibody

ATG4C MaxPab polyclonal antibody. Western Blot analysis of ATG4C expression in human kidney. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

APG4C / ATG4C antibody

ATG4C MaxPab polyclonal antibody. Western Blot analysis of ATG4C expression in human kidney. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

APG4C / ATG4C antibody

Confocal microscopy on immunofluorescently detected ATG4C in HL-60 cell line using rabbit ATG4C polyclonal antibody ( Cat # PAB0737 ) at a dilution of 1 : 100, incubated for 1 hr at room temperature. The cells stained for ATG4C appear in red. The cells were then counter stained with Hoechst Dye ( blue colour ) . Here, the merged picture is presented. Rabbit Hu, Rt C, ICC/IF, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

APG4C / ATG4C antibody

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using ATG4C Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

APG4C / ATG4C antibody

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using ATG4C Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

APG4C / ATG4C antibody

APG4C / ATG4C Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

APG4C / ATG4C antibody

APG4C / ATG4C Sheep IgG Purified Hu, Ms, Rt C, P, WB
0.5 mg / €400.00
  Novus Biologicals Inc.

APG4C / ATG4C antibody

APG4C / ATG4C Rabbit IgG Aff - Purified Hu E, ICC/IF, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

APG4C / ATG4C antibody

APG4C / ATG4C Rabbit IgG Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

APG4C / ATG4C antibody

Immunohistochemistry-Paraffin: ATG4C Antibody [NBP1-89043] - Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APG4C / ATG4C (transcript variant 8)

APG4C / ATG4C Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APG4C / ATG4C (transcript variant 7)

APG4C / ATG4C Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APG4C / ATG4C (transcript variant 7)

APG4C / ATG4C Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

APG4C / ATG4C

APG4C / ATG4C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

APG4C / ATG4C

APG4C / ATG4C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ATG4C 293T Cell Transient Overexpression Lysate(Denatured)

ATG4C 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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