APG4C / ATG4C antibody

Principal name

APG4C / ATG4C antibody

Alternative names for APG4C / ATG4C antibody

Autophagin-3, AUTL1, AUTL3, Cysteine protease ATG4C, Autophagy-related protein 4 homolog C, Autophagy-related cysteine endopeptidase 3, AUT-like 3 cysteine endopeptidase

SwissProt ID

Q811C2 (Mouse), Q96DT6 (Human)

Gene ID

84938 (ATG4C), 242557 (Atg4c)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), Can (Canine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of APG4C / ATG4C antibody

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. It is highly expressed in skeletal muscle, heart, liver and testis.

General readings

"Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy." Marino G., Uria J.A., Puente X.S., Quesada V., Bordallo J., Lopez-Otin C. J. Biol. Chem. 278:3671-3678(2003)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APG4C / ATG4C antibody

  Rabbit polyclonal anti-ATG4C antibody  
Western blot analysis of extracts from K562 cells and COS7 cells, using ATG4C antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APG4C / ATG4C (C-term) antibody

  Goat Polyclonal Anti-ATG4C Antibody  
ATG4C antibody (2µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APG4C / ATG4C antibody

  Rabbit Polyclonal Anti-ATG4C Antibody - middle region  
WB Suggested Anti-ATG4C Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 721_B cell lysate Rabbit Aff - Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

APG4C / ATG4C antibody

  Rabbit Polyclonal Anti-ATG4C Antibody  
Western blot analysis of ATG4C in A549 cell lysate with ATG4C antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APG4C / ATG4C antibody

  Rabbit Polyclonal Anti-ATG4C Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Mouse brain tissue, Primary antibody: (ATG4C Antibody) at dilution 1/275, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APG4C / ATG4C antibody

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using ATG4C Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

APG4C / ATG4C antibody

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using ATG4C Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Atg4c - mouse gene knockout kit via CRISPR

Atg4c - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Atg4c - mouse gene knockout kit via CRISPR

Atg4c - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Atg4c - mouse gene knockout kit via CRISPR

Atg4c - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Atg4c - mouse gene knockout kit via CRISPR

Atg4c - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APG4C / ATG4C (transcript variant 8)

  Recombinant protein of human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 8  
APG4C / ATG4C Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APG4C / ATG4C (transcript variant 7)

  Recombinant protein of human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 7  
APG4C / ATG4C Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APG4C / ATG4C (transcript variant 7)

  Recombinant protein of human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 7  
APG4C / ATG4C Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ATG4C overexpression lysate

ATG4C overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ATG4C (mGFP-tagged) - Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ATG4C (mGFP-tagged) - Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ATG4C (mGFP-tagged) - Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ATG4C (mGFP-tagged) - Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ATG4C (Myc-DDK tagged) - Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ATG4C (Myc-DDK tagged) - Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, ATG4C (Myc-DDK tagged) - Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ATG4C (Myc-DDK tagged) - Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Atg4c (GFP-tagged) - Mouse autophagy-related 4C (yeast) (Atg4c), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Atg4c (GFP-tagged) - Mouse autophagy-related 4C (yeast) (Atg4c), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,060.00
  OriGene Technologies, Inc.

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