APG4D / ATG4D antibody

Principal name

APG4D / ATG4D antibody

Alternative names for APG4D / ATG4D antibody

AUTL4, Autophagin-4, Cysteine protease ATG4D, Autophagy-related protein 4 homolog D, Autophagy-related cysteine endopeptidase 4, AUT-like 4 cysteine endopeptidase

SwissProt ID

Q684M2 (Pig), Q86TL0 (Human), Q8BGV9 (Mouse)

Gene ID

84971 (ATG4D), 235040 (Atg4d)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of APG4D / ATG4D antibody

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. APG4C is mainly expressed in skeletal muscle and, to a lower extent, in testis.

General readings

"Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy." Marino G., Uria J.A., Puente X.S., Quesada V., Bordallo J., Lopez-Otin C. J. Biol. Chem. 278:3671-3678(2003)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APG4D / ATG4D (227-257) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

APG4D / ATG4D antibody

  Rabbit polyclonal anti-ATG4D antibody  
Western blot analysis of extracts from K562 cells, using ATG4D antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APG4D / ATG4D antibody

  Mouse monoclonal ATG4D Antibody  
ATG4D/MB10250 antibody (Cat. #TA324341) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ATG4D/MB10250  antibody detected the ATG4D/MB10250  protein (arrow). Mouse IgG1 222CT15.4.1 Purified Hu ICC/IF, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

APG4D / ATG4D antibody

  Rabbit Polyclonal Anti-ATG4D Antibody - middle region  
WB Suggested Anti-ATG4D Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HCT15 cell lysate Rabbit Aff - Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

APG4D / ATG4D antibody

  Rabbit Polyclonal Anti-ATG4D Antibody  
Western blot analysis of ATG4D in human testis tissue lysate with ATG4D antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APG4D / ATG4D antibody

  Rabbit Polyclonal Anti-ATG4D Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (ATG4D Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

APG4D / ATG4D (N-term) antibody

Formalin Fixed, Paraffin Embedded Human skeletal muscle stained with ATG4D Antibody (N-term) Cat.-No AP32159PU-N followed by peroxidase conjugation to the secondary antibody and DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

APG4D / ATG4D antibody

APG4D / ATG4D Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

Atg4d - mouse gene knockout kit via CRISPR

Atg4d - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Atg4d - mouse gene knockout kit via CRISPR

Atg4d - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Atg4d - mouse gene knockout kit via CRISPR

Atg4d - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Atg4d - mouse gene knockout kit via CRISPR

Atg4d - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APG4D / ATG4D

APG4D / ATG4D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

APG4D / ATG4D

APG4D / ATG4D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ATG4D (mGFP-tagged)-Human ATG4 autophagy related 4 homolog D (S. cerevisiae) (ATG4D), 200 uL, >10^7 TU/mL

Lenti ORF particles, ATG4D (mGFP-tagged)-Human ATG4 autophagy related 4 homolog D (S. cerevisiae) (ATG4D), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ATG4D (Myc-DDK-tagged)-Human ATG4 autophagy related 4 homolog D (S. cerevisiae) (ATG4D), 200 uL, >10^7 TU/mL

Lenti ORF particles, ATG4D (Myc-DDK-tagged)-Human ATG4 autophagy related 4 homolog D (S. cerevisiae) (ATG4D), 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Atg4d (GFP-tagged) - Mouse autophagy-related 4D (yeast) (Atg4d), 200 uL, >10^7 TU/mL

Lenti ORF particles, Atg4d (GFP-tagged) - Mouse autophagy-related 4D (yeast) (Atg4d), 200 uL, >10^7 TU/mL  
200 µl / €1,080.00
  OriGene Technologies, Inc.

Lenti ORF particles, Atg4d (Myc-DDK-tagged) - Mouse autophagy-related 4D (yeast) (Atg4d), 200 uL, >10^7 TU/mL

Lenti ORF particles, Atg4d (Myc-DDK-tagged) - Mouse autophagy-related 4D (yeast) (Atg4d), 200 uL, >10^7 TU/mL  
200 µl / €970.00
  OriGene Technologies, Inc.

18 Item(s)

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