APIP antibody

Principal name

APIP antibody

Alternative names for APIP antibody

APAF1-interacting protein, CGI-29

SwissProt ID

Q5ZLP2 (Chick), Q96GX9 (Human), Q9WVQ5 (Mouse)

Gene ID

51074 (APIP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of APIP antibody

The mammalian homologues of the key cell death gene CED-4 in C. elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease-activating factor 1) (1,2). Apaf1 binds to cytochrome c (Apaf2) and caspase-9 (Apaf3), which leads to caspase-9 activation. Activated caspase-9 in turn cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis (3). Recently, Cho et al (4) have identified a new Apaf-1 Interactiong Protein (APIP) also known as CG129 and MMRP19, as a negative regulator of ischemic injury. APIP competes with Caspase-9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an alternative splicing variant differing in its N-terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney.

General readings

Cho D.-H., et al. (2004) J. Biol. Chem. 279:39942-39950Lai C.-H., et al. (2000) Genome Res. 10:703-713

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19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APIP antibody

Western Blot: APIP Antibody (19F461) [TA336411] - WB analysis of APIP2 in (A) recombinant protein and (B) HeLa cell lysate using APIP antibody at 2 ug/ml. Mouse IgG2b 19F461 Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APIP antibody

Predicted band size: 27 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 60 ug Primary antibody: 1/200 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APIP antibody

Predicted band size: 27 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 60 ug Primary antibody: 1/300 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APIP antibody

WB Suggested Anti-APIP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 721_B cell lysateAPIP is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

APIP antibody

Host: Rabbit; Target Name: APIP; Sample Tissue: MCF7 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

APIP (full length) antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

APIP antibody

Western blot analysis of APIP in A ) recombinant protein, B ) HeLa, and C ) 293 whole cell lysate. Using APIP monoclonal antibody, clone 19F461 ( Cat # MAB0105 ) at 2 µg/ml. Mouse IgG2b 19F461 Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

APIP antibody

Western blot analysis of APIP in human muscle. Using APIP polyclonal antibody ( Cat # PAB0219 ) at 2 µg/ml. Rabbit Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

APIP antibody

Human 721_B; WB Suggested Anti-APIP Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 721_B cell lysate. APIP is supported by BioGPS gene expression data to be expressed in 721_B.; APIP antibody - middle region (ARP56789_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

APIP antibody

Western Blot: APIP Antibody (19F424) [NB100-56568] - Western blot analysis of APIP in recombinant protein using NB100-56568 at 2 ug/ml. Mouse 19F424 Aff - Purified Hu WB
0.1 mg / €320.00
  Novus Biologicals Inc.

APIP antibody

Western  Blot:  APIP Antibody [NBP1-33505] – Western blot analysis of APIP on Molt-4 (Lane A) and Raji (Lane B) lysates using NBP1-33505 at a dilution of 1:1000. 30ug whole cell lysate loaded on 12% SDS PAGE gel. Rabbit IgG Hu WB
0.1 ml / €420.00
  Novus Biologicals Inc.

APIP antibody

Immunohistochemistry-Paraffin: APIP Antibody [NBP1-89039] - Immunohistochemical staining of human kidney shows cytoplasmic and nuclear positivity in tubular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

APIP antibody

Immunohistochemistry-Paraffin: APIP Antibody [NBP1-89040] - Immunohistochemical staining of human stomach shows strong nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APIP

APIP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APIP (1-242, His-tag)

APIP Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

APIP (1-242, His-tag)

APIP Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

APIP

APIP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

APIP

APIP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

APIP overexpression lysate

APIP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

19 Item(s)

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