APIP antibody

Principal name

APIP antibody

Alternative names for APIP antibody

APAF1-interacting protein, CGI-29

SwissProt ID

Q5ZLP2 (Chick), Q96GX9 (Human), Q9WVQ5 (Mouse)

Gene ID

51074 (APIP), 56369 (Apip)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of APIP antibody

The mammalian homologues of the key cell death gene CED-4 in C. elegans has been identified recently from human and mouse and desigted Apaf1 (for apoptosis protease-activating factor 1). Apaf1 binds to cytochrome c (Apaf2) and caspase-9 (Apaf3), which leads to caspase-9 activation. Activated caspase-9 in turn cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis3. Recently, Cho et al have identified a new Apaf-1 Interactiong Protein (APIP) also known as CG129 and MMRP19, as a negative regulator of ischemic injury. APIP competes with Caspase-9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an altertive splicing variant differing in its N-terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney.

General readings

Cho D.-H., et al. (2004) J. Biol. Chem. 279:39942-39950Lai C.-H., et al. (2000) Genome Res. 10:703-713

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18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APIP antibody

  Mouse Monoclonal APIP Antibody (19F461)  
Western Blot: APIP Antibody (19F461) [TA336411] - WB analysis of APIP2 in (A) recombinant protein and (B) HeLa cell lysate using APIP antibody at 2 ug/ml. Mouse IgG2b 19F461 Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APIP antibody

  Anti-APIP Rabbit Polyclonal Antibody  
Predicted band size: 27 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 60 ug Primary antibody: 1/200 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APIP antibody

  Anti-APIP Rabbit Polyclonal Antibody  
Predicted band size: 27 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 60 ug Primary antibody: 1/300 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APIP antibody

  Rabbit Polyclonal Anti-APIP Antibody - middle region  
WB Suggested Anti-APIP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 721_B cell lysateAPIP is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

APIP antibody

  Rabbit Polyclonal Anti-APIP Antibody - N-terminal region  
Host: Rabbit; Target Name: APIP; Sample Tissue: MCF7 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

APIP (full length) antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Apip - mouse gene knockout kit via CRISPR

Apip - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Apip - mouse gene knockout kit via CRISPR

Apip - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Apip - mouse gene knockout kit via CRISPR

Apip - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Apip - mouse gene knockout kit via CRISPR

Apip - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APIP

  Recombinant protein of human APAF1 interacting protein (APIP)  
APIP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APIP (1-242, His-tag)

APIP Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

APIP (1-242, His-tag)

APIP Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

APIP overexpression lysate

APIP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, APIP (mGFP-tagged) - Human APAF1 interacting protein (APIP), 200 uL, >10^7 TU/mL

Lenti ORF particles, APIP (mGFP-tagged) - Human APAF1 interacting protein (APIP), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, APIP (Myc-DDK tagged) - Human APAF1 interacting protein (APIP) , 200 uL, >10^7 TU/mL

Lenti ORF particles, APIP (Myc-DDK tagged) - Human APAF1 interacting protein (APIP) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Apip (GFP-tagged) - Mouse APAF1 interacting protein (Apip), 200 uL, >10^7 TU/mL

Lenti ORF particles, Apip (GFP-tagged) - Mouse APAF1 interacting protein (Apip), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Apip (Myc-DDK-tagged) - Mouse APAF1 interacting protein (Apip), 200 uL, >10^7 TU/mL

Lenti ORF particles, Apip (Myc-DDK-tagged) - Mouse APAF1 interacting protein (Apip), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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