APOBEC1 complementation factor antibody

Principal name

APOBEC1 complementation factor antibody

Alternative names for APOBEC1 complementation factor antibody

A1CF, ACF, ASP

SwissProt ID

Q5YD48 (Mouse), Q923K9 (Rat), Q9NQ94 (Human)

Gene ID

29974 (A1CF), 170912 (A1cf)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of APOBEC1 complementation factor antibody

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.

General readings

Blanc,V., (2005) Mol. Cell. Biol. 25 (16), 7260-7269

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APOBEC1 complementation factor antibody

  Rabbit Polyclonal Anti-A1CF Antibody  
WB Suggested Anti-A1CF Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Spleen Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

APOBEC1 complementation factor antibody

  Rabbit Polyclonal Anti-A1CF Antibody  
Host: Rabbit; Target Name: A1CF; Sample Tissue: Liver Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

APOBEC1 complementation factor antibody

  Rabbit Polyclonal Anti-A1CF Antibody  
Host: Rabbit; Target Name: A1CF; Sample Tissue: Human Adult Placenta; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

APOBEC1 complementation factor (C-term) antibody

ACF Antibody (C-term) (Cat. #AP50047PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ACF Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

A1CF - human gene knockout kit via CRISPR

A1CF - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

A1CF - human gene knockout kit via CRISPR

A1CF - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

A1CF - human gene knockout kit via CRISPR

A1CF - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

A1CF - human gene knockout kit via CRISPR

A1CF - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APOBEC1 complementation factor (transcript variant 2)

  Recombinant protein of human APOBEC1 complementation factor (A1CF), transcript variant 2  
APOBEC1 complementation factor Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APOBEC1 complementation factor (transcript variant 3)

  Recombinant protein of human APOBEC1 complementation factor (A1CF), transcript variant 3  
APOBEC1 complementation factor Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, A1CF (mGFP-tagged)-Human APOBEC1 complementation factor (A1CF), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, A1CF (mGFP-tagged)-Human APOBEC1 complementation factor (A1CF), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,230.00
  OriGene Technologies, Inc.

Lenti ORF particles, A1CF (mGFP-tagged) - Human APOBEC1 complementation factor (A1CF), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, A1CF (mGFP-tagged) - Human APOBEC1 complementation factor (A1CF), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, A1CF (mGFP-tagged) - Human APOBEC1 complementation factor (A1CF), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, A1CF (mGFP-tagged) - Human APOBEC1 complementation factor (A1CF), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, A1CF (mGFP-tagged)-Human APOBEC1 complementation factor (A1CF), transcript variant 5, 200 uL, >10^7 TU/mL

Lenti ORF particles, A1CF (mGFP-tagged)-Human APOBEC1 complementation factor (A1CF), transcript variant 5, 200 uL, >10^7 TU/mL  
200 µl / €1,250.00
  OriGene Technologies, Inc.

Lenti ORF particles, A1CF (Myc-DDK-tagged)-Human APOBEC1 complementation factor (A1CF), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, A1CF (Myc-DDK-tagged)-Human APOBEC1 complementation factor (A1CF), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,100.00
  OriGene Technologies, Inc.

Lenti ORF particles, A1CF (Myc-DDK tagged) - Human APOBEC1 complementation factor (A1CF), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, A1CF (Myc-DDK tagged) - Human APOBEC1 complementation factor (A1CF), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, A1CF (Myc-DDK tagged) - Human APOBEC1 complementation factor (A1CF), transcript variant 3 , 200 uL, >10^7 TU/mL

Lenti ORF particles, A1CF (Myc-DDK tagged) - Human APOBEC1 complementation factor (A1CF), transcript variant 3 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, A1CF (Myc-DDK-tagged)-Human APOBEC1 complementation factor (A1CF), transcript variant 5, 200 uL, >10^7 TU/mL

Lenti ORF particles, A1CF (Myc-DDK-tagged)-Human APOBEC1 complementation factor (A1CF), transcript variant 5, 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, A1cf (GFP-tagged ORF) - Rat APOBEC1 complementation factor (A1cf), 200 uL, >10^7 TU/mL

Lenti ORF particles, A1cf (GFP-tagged ORF) - Rat APOBEC1 complementation factor (A1cf), 200 uL, >10^7 TU/mL  
200 µl / €1,230.00
  OriGene Technologies, Inc.

Lenti ORF particles, A1cf (Myc-DDK-tagged ORF) - Rat APOBEC1 complementation factor (A1cf), 200 uL, >10^7 TU/mL

Lenti ORF particles, A1cf (Myc-DDK-tagged ORF) - Rat APOBEC1 complementation factor (A1cf), 200 uL, >10^7 TU/mL  
200 µl / €1,104.00
  OriGene Technologies, Inc.

20 Item(s)

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