APOBEC3C antibody

Principal name

APOBEC3C antibody

Alternative names for APOBEC3C antibody

APOBEC1L, PBI, APOBEC1-like, Phorbolin I protein, APOBEC-3C, Probable DNA dC->dU-editing enzyme APOBEC-3C, Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C

SwissProt ID

Q9NRW3 (Human)

Gene ID

27350 (APOBEC3C)

Available reactivities

Hu (Human)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of APOBEC3C antibody

APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.

General readings

Baumert TF, Rosler C, Malim MH, von Weizsacker F.
Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C.
Hepatology. 2007 Sep;46(3):682-9.
PMID: 17625792

14 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APOBEC3C (C-term) antibody

TA303327 (0.5µg/ml) staining of Daudi lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APOBEC3C antibody

Western blot analysis of IM9 cells (Lane 1: 48ug lysate) and ECL cells (Lane 2: 50ug lysate) with anti-APOBEC3C antibody diluated at 1:1000. (Predicted and observed size: 23kDa) Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

APOBEC3C antibody

Western Blot analysis of APOBEC3C expression in transfected 293T cell line (H00027350-T01) by APOBEC3C MaxPab polyclonal antibody.

Lane 1: APOBEC3C transfected lysate(20.9 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

APOBEC3C antibody

APOBEC3C Rabbit Serum Hu IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

APOBEC3C antibody

Western Blot analysis of APOBEC3C expression in transfected 293T cell line (H00027350-T01) by APOBEC3C MaxPab polyclonal antibody.

Lane 1: APOBEC3C transfected lysate(22.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

APOBEC3C antibody

APOBEC3C Mouse IgG2a 3E6 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

APOBEC3C antibody

NBP1-00131(0.5ug/ml) staining of Daudi lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APOBEC3C

APOBEC3C Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

APOBEC3C

APOBEC3C Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

APOBEC3C

APOBEC3C Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

APOBEC3C

APOBEC3C Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

APOBEC3C (Human) IP-WB Antibody Pair

APOBEC3C (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

APOBEC3C (Human) IP-WB Antibody Pair

APOBEC3C (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

APOBEC3C 293T Cell Transient Overexpression Lysate(Denatured)

APOBEC3C 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

14 Item(s)

per page
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