Apolipoprotein A I / APO AI antibody

Principal name

Apolipoprotein A I / APO AI antibody

Alternative names for Apolipoprotein A I / APO AI antibody

APOA1, ApoA-I, Apo-AI, ApoAI

SwissProt ID

P02647 (Human), P02648 (Canfa), P04639 (Rat), P08250 (Chick), P15497 (Bovin), P18648 (Pig), Q00623 (Mouse), Q9Z2L4 (Mesau)

Gene ID

335 (APOA1), 25081 (Apoa1), 11806

Available reactivities

Hu (Human), Hst (Hamster), Ms (Mouse), Rt (Rat), Chk (Chicken)

Available hosts

Mouse, Rabbit, Goat, Sheep, Chicken

Available applications

Enzyme Immunoassay (E), Radioimmunoassay (R), Immunodiffusion (ID), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoelectrophoresis (Ie), Radial Immunodiffusion (RID), Frozen Sections (C), Immunoprecipitation (IP), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Apolipoprotein A I / APO AI antibody

Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterol-acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease.
The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.

General readings

1. Thomson, R. et al. (2009) Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes.
Proc. Natl. Acad. Sci. USA. 106: 19509-14.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Apolipoprotein A I / APO AI antibody

R1029P Apolipoprotein AI antibody staining of Paraffin-Embedded Human Liver. Goat Purified Hu C, E, IP, P, WB
1 mg / €1,180.00
  OriGene Technologies GmbH

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