Apolipoprotein A V / ApoA5 antibody

Principal name

Apolipoprotein A V / ApoA5 antibody

Alternative names for Apolipoprotein A V / ApoA5 antibody

Apolipoprotein A-V, Apo-AV, ApoA-V, RAP3, Regeneration-associated protein 3

SwissProt ID

Q6Q788 (Human), Q8C7G5 (Mouse), Q9QUH3 (Rat)

Gene ID

116519 (APOA5)

Available reactivities

Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Apolipoprotein A V / ApoA5 antibody

Apolipoprotein A V is a minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. It may also be associated with chylomicrons. It is an important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Apolipoprotein A V activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.
Apolipoprotein A V is upregulated by PPARA agonists, which are used clinically to lower serum TG (such as fibrates). It is induced in early phase of liver regeneration.
Defects in Apolipoprotein A V gene are a cause of susceptibility to familial hypertriglyceridemia. It is a coronary heart disease risk factor. On a regular diet the patient demonstrates increased plasma VLDL. Plasma triglycerides are persistently increased, while plasma cholesterol and phospholipids are usually within normal limits.

General readings

Corella D, Lai CQ, Demissie S, Cupples LA, Manning AK, Tucker KL, Ordovas JM.
APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study.
J Mol Med. 2007 Feb;85(2):119-28. Epub 2007 Jan 9.
PMID: 17211608

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Apolipoprotein A V / ApoA5 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-APOA5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507140) Mouse IgG1 OTI1A1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Apolipoprotein A V / ApoA5 antibody

Western Blot: Apolipoprotein A5 Antibody (1G5G9 (c),2G1H11G9B3) [NBP1-47550] - Western blot analysis using anti-Apoa5 monoclonal antiobdy against human serum. Mouse IgG1 1G5G9 (c),2G1H11G9B3 Aff - Purified Hu E, WB
0.1 mg / €510.00
  Novus Biologicals Inc.

Apolipoprotein A V / ApoA5 antibody

Western blot analysis using anti- human APOA5 monoclonal antibody against human serum total protein (lane 2). Lane 1 is a MW standard Mouse IgG1 1G5G9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Apolipoprotein A V / ApoA5 antibody

TA303257 (0.3µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Apolipoprotein A V / ApoA5 antibody

Western blot analysis of extracts from 293 cells, using APOA5 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Apolipoprotein A V / ApoA5 antibody

Western Blot: Apolipoprotein A5 Antibody (1G5G9) [TA336521] - Analysis of ApoA5 in HepG2 lysates Mouse IgG1 1G5G9 Purified Hu C, E, F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Apolipoprotein A V / ApoA5 antibody

Immunocytochemistry/Immunofluorescence: Apolipoprotein A5 Antibody (4H8H8E2) [TA336523] - Apolipoprotein A5 antibody (1:250) was tested in HepG2 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 Mouse IgG1 4H8H8E2 Purified Hu E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

Apolipoprotein A V / ApoA5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (RC211023, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5. Mouse IgG1 OTI1G4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Apolipoprotein A V / ApoA5 antibody

Immunofluorescent staining of HeLa cells using anti-APOA5 mouse monoclonal antibody (TA507094). Mouse IgG1 OTI1E3 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Apolipoprotein A V / ApoA5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (RC211023, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5. Mouse IgG1 OTI1B4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Apolipoprotein A V / ApoA5 antibody

Anti-APOA5 mouse monoclonal antibody (TA507101) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY APOA5(RC211023). Mouse IgG1 OTI2B11 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Apolipoprotein A V / ApoA5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (RC211023, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5. Mouse IgG1 OTI1H4 Purified Hu, Mky, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Apolipoprotein A V / ApoA5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (RC211023, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5. Mouse IgG1 OTI1A2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Apolipoprotein A V / ApoA5 antibody

Anti-APOA5 mouse monoclonal antibody (TA507164) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY APOA5(RC211023). Mouse IgG1 OTI1D1 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Apolipoprotein A V / ApoA5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (RC211023, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5. Mouse IgG1 OTI3A5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Apolipoprotein A V / ApoA5 antibody

Apolipoprotein A V / ApoA5 Mouse IgG1 4H8H8E2 (c) Ascites Hu E, WB
0.1 ml / €480.00
  Acris Antibodies GmbH

Apolipoprotein A V / ApoA5 antibody

Western blot analysis using ApoA5 antibody Cat.-No AM06076PU-N against human serum (Lane 1) and ApoA5 recombinant protein (Lane 2). Mouse IgG1 1G5G9 (c) Purified Hu E, WB
0.1 ml / €480.00
  Acris Antibodies GmbH

Apolipoprotein A V / ApoA5 (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with APOA5 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Apolipoprotein A V / ApoA5 control peptide

Apolipoprotein A V / ApoA5
50 µg / €160.00
  Acris Antibodies GmbH

Apolipoprotein A V / ApoA5 (C-term) antibody

Western blot analysis of ApoA5 in human liver tissue lysate with ApoA5 antibody at 1 μg/ml. Rabbit Aff - Purified Chk, Hu E, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

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