Apolipoprotein C I / ApoC1 antibody

Principal name

Apolipoprotein C I / ApoC1 antibody

Alternative names for Apolipoprotein C I / ApoC1 antibody

Apolipoprotein C-I, Apolipoprotein C1, Apo-CI, ApoC-I

SwissProt ID

P02654 (Human), P19939 (Rat), P33047 (Rabit), P34928 (Mouse), P56595 (Canfa)

Gene ID

341 (APOC1), 11812 (Apoc1)

Available reactivities

Hu (Human)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Frozen Sections (C), Immunoprecipitation (IP)

Background of Apolipoprotein C I / ApoC1 antibody

The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Apolipoprotein C-I appears to modulate the interaction of APOE with beta migrating VLDL and inhibit binding of beta VLDL to the LDL receptor related protein.
At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL).

General readings

1. Berbee JF, van der Hoogt CC, Sundararaman D, Havekes LM, Rensen PC. Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-Iinduced inhibition of LPL. J Lipid Res. 2005 Feb;46(2):297-306. Epub 2004 Dec 1.
PMID: 15576844

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Apolipoprotein C I / ApoC1 (C-term) antibody

  Goat Anti-APOC1 Antibody  
TA305838 (3.8ug/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Hu P
0.1 mg / €325.00
  OriGene Technologies, Inc.

Apolipoprotein C I / ApoC1 antibody

  Rabbit anti-APOC1 Polyclonal Antibody  
Western blot analysis of extracts of Recombinant Protein cell line, using APOC1 antibody. Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Apolipoprotein C I / ApoC1 antibody

  Rabbit Polyclonal Anti-APOC1 Antibody  
Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal liver tissue, Primary antibody: (APOC1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Apolipoprotein C I / ApoC1 antibody

Human Liver (formalin-fixed, paraffin-embedded) stained with APOC1 antibody AP22484PU-N at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat IgG Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Apolipoprotein C I / ApoC1 antibody

Apolipoprotein C I / ApoC1 Rabbit Aff - Purified Hu E, WB
0.5 mg / €460.00
  Acris Antibodies GmbH

Apolipoprotein C I / ApoC1 antibody

Apolipoprotein C I / ApoC1 Goat HRP Hu E, WB
0.5 ml / €520.00
  Acris Antibodies GmbH

Apolipoprotein C I / ApoC1 antibody

Apolipoprotein C I / ApoC1 Goat IgG Purified Hu C, E, IP, P, WB
1 mg / €1,180.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

APOC1 - human gene knockout kit via CRISPR

APOC1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

APOC1 - human gene knockout kit via CRISPR

APOC1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

APOC1 - human gene knockout kit via CRISPR

APOC1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

APOC1 - human gene knockout kit via CRISPR

APOC1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Apoc1 - mouse gene knockout kit via CRISPR

Apoc1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Apoc1 - mouse gene knockout kit via CRISPR

Apoc1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Apoc1 - mouse gene knockout kit via CRISPR

Apoc1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Apoc1 - mouse gene knockout kit via CRISPR

Apoc1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Apolipoprotein C I / ApoC1

  Recombinant protein of human apolipoprotein C-I (APOC1)  
Apolipoprotein C I / ApoC1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Apolipoprotein C I / ApoC1 (27-83, His-tag)

Apolipoprotein C I / ApoC1 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

Apolipoprotein C I / ApoC1 (27-83, His-tag)

Apolipoprotein C I / ApoC1 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Apolipoprotein C I / ApoC1

Apolipoprotein C I / ApoC1 Human Purified > 95 % Plasma
0.1 mg / €230.00
  Acris Antibodies GmbH

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Apoc1 (GFP-tagged) - Mouse apolipoprotein C-I (Apoc1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Apoc1 (GFP-tagged) - Mouse apolipoprotein C-I (Apoc1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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