APPBP1 antibody

Principal name

APPBP1 antibody

Alternative names for APPBP1 antibody

NAE1, HPP1, Amyloid protein-binding protein 1, Amyloid beta precursor protein-binding protein 1

SwissProt ID

Q13564 (Human), Q8VBW6 (Mouse), Q9Z1A5 (Rat)

Gene ID

8883 (NAE1)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C)

Background of APPBP1 antibody

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (3) lacks an alternate exon compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Jung, A.C., et al. Int. J. Cancer 126(8):1882-1894(2010)
Park, Y., et al. Biochem. Biophys. Res. Commun. 374(2):294-298(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)
Li, T., et al. Arch. Biochem. Biophys. 453(1):70-74(2006)
Norman, J.A., et al. Biochemistry 45(9):3014-3019(2006)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

APPBP1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-NAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804384) Mouse IgG1 OTI1E10 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APPBP1 (C-term) antibody

Western blot analysis of anti-APPBP1 Antibody (C-term) (Cat.#TA300061) in mouse brain tissue lysates (35ug/lane). APPBP1(arrow) was detected using the purified Pab. Rabbit Ig Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

APPBP1 antibody

Host: Rabbit; Target Name: Nae1; Sample Tissue: Mouse Lung lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

APPBP1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NAE1 (RC201326, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NAE1. Mouse IgG2b OTI1A10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APPBP1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NAE1 (RC201326, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NAE1. Mouse IgG2a OTI1B2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APPBP1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NAE1 (RC201326, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NAE1. Mouse IgG1 OTI1A8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APPBP1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NAE1 (RC201326, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NAE1. Mouse IgG2b OTI1D12 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APPBP1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NAE1 (RC201326, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NAE1. Mouse IgG1 OTI1E9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

APPBP1 (C-term) antibody

Formalin-fixed and paraffin-embedded human testis tissue reacted with APPBP1 antibody (C-term) (AP13996PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

APPBP1 (Center) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with APPBP1 Antibody (Center) Cat.-No AP52806PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

APPBP1 antibody

APPBP1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

APPBP1 antibody

APPBP1 MaxPab polyclonal antibody. Western Blot analysis of APPBP1 expression in rat brain. Mouse Purified Hu, Rt E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

APPBP1 antibody

APPBP1 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

APPBP1 antibody

APPBP1 monoclonal antibody (M01), clone 4E8-H3 Western Blot analysis of APPBP1 expression in HeLa ( Cat # L013V1 ). Mouse IgG2a 4E8-H3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

APPBP1 antibody

APPBP1 Mouse IgG2a 4E8-H3 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

APPBP1 antibody

APPBP1 Mouse IgG2a 2E9-D12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

APPBP1 antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with NAE1 polyclonal antibody ( Cat # PAB2845 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

APPBP1 antibody

Immunohistochemistry-Paraffin: NAE1 Antibody [NBP1-92162] - Immunohistochemical staining of human cerebellum shows strong nuclear positivity in Purkinje cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

APPBP1 antibody

Immunohistochemistry-Paraffin: NAE1 Antibody [NBP1-92163] - Immunohistochemical staining of human testis shows strong nuclear and cytoplasmic positivity in cells of seminiferus ducts. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

APPBP1 (transcript variant 3)

APPBP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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