Aquaporin-3 / AQP3 antibody

Principal name

Aquaporin-3 / AQP3 antibody

Alternative names for Aquaporin-3 / AQP3 antibody

AQP-3

SwissProt ID

P47862 (Rat), Q08DE6 (Bovin), Q8R2N1 (Mouse), Q92482 (Human)

Gene ID

360 (AQP3), 65133 (Aqp3)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Sh (Sheep), Mky (Monkey), Por (Porcine), Ze (Zebrafish)

Available hosts

Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of Aquaporin-3 / AQP3 antibody

Water channel proteins, known as aquaporins, are transmembrane proteins that mediate osmotic water permeability. The discovery of aquaporin (AQP) has made a great impact on life sciences. AQPs are a family of homologous water channels widely distributed in plants, unicellular organisms, invertebrates, and vertebrates. Aquaporins are selective water/glycerol channels involved in the maintenance of volume homeostasis and ionic/osmotic balance. These water channels also enhance cellular tolerance against rapid freezing, which suggest that they might have some ecological relevance also. Early work of Nobel Prize winner, Peter Agre and his group first clone a 269 amio acid protein from RBC and kidney libraries that has a 6 TMD (1). The amino terminal end of the protein was in the membrane and has 2 repeats that are at 180oto each other and are responsible for water selectivity. Now there are atlest 12 isoforms of Aquaporins area cloned.
Acetazolamide can bind to Aquaporin 1 and inhibit the water movement across the plasma membrane. In brain, three main AQPs AQP1, AQP4 and AQP9 are expressed and are implicated in numerous physiological functions. AQP1 has a role in cerebrospinal fluid formation, whereas AQP4 is involved in water homeostasis and extracellular osmotic pressure in brain parenchyma. AQP4 seems also to have an important function in oedema formation after brain trauma or brain ischemia. AQP9 is implicated in brain energy metabolism (2). AQP1 and 4 are also implicated in water balance in retina and other eye components. Studies also suggest that AQP1 may be responsible for the high vascular permeability and interstitial fluid pressure in tumors of the brain, colon, breast and pancreas. AQP1 may also play a role in tumor angiogenesis and in the development of effusions or edema fluid.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Aquaporin-3 / AQP3 (267-292, C-term) antibody

Western blot analysis of Aquaporin 3 in rat kidney lysates using a 1 in 2000 dilution of the antibody Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aquaporin-3 / AQP3 antibody

Anti-AQP3 / Aquaporin 3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml. Rabbit IgG Purified Hu, Ms, Rt P
50 µl / €345.00
  OriGene Technologies, Inc.

Aquaporin-3 / AQP3 antibody

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using AQP3 Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aquaporin-3 / AQP3 antibody

Western blot analysis of rat kidney membranes: 1. Anti-Aquaporin 3 antibody , (1:200). 2. Anti-Aquaporin 3 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Aquaporin-3 / AQP3 control peptide

Aquaporin-3 / AQP3
0.25 mg / €250.00
  Acris Antibodies GmbH

Aquaporin-3 / AQP3 (C-term amidated) antibody

Western blot with AP09889PU-N at 1:500. Rabbit Aff - Purified Bov, Hu, Ms, Rt, Sh E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Aquaporin-3 / AQP3 antibody

Immunohistochemical analysis in paraffin-embedded human lung carcinoma tissue using Aquaporin-3 antibody (Cat.-No. AP20765PU-N). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Aquaporin-3 / AQP3 antibody

Aquaporin-3 / AQP3 Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €290.00
  Boster Immunoleader

Aquaporin-3 / AQP3 antibody

Immunohistochemical analysis of Aquaporin 3 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Por, Rt, Sh, Ze P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Aquaporin-3 / AQP3 antibody

Immunohistochemical analysis of Aquaporin 3 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Por, Rt, Sh, Ze P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Aquaporin-3 / AQP3 antibody

Immunohistochemical analysis of Aquaporin 3 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Por, Rt, Sh, Ze P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Aquaporin-3 / AQP3 antibody

Aquaporin-3 / AQP3 Rabbit Purified Hu WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Aquaporin-3 / AQP3 antibody

Aquaporin-3 / AQP3 Rabbit Aff - Purified Hu, Ms, Rt P
0.1 mg / €420.00
  Novus Biologicals Inc.

Aquaporin-3 / AQP3 antibody

Aquaporin-3 / AQP3 Goat Purified Ms, Rt P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Aquaporin-3 / AQP3

Aquaporin-3 / AQP3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

AQP3 overexpression lysate

AQP3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

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