Aquaporin-5 / AQP5 antibody

Principal name

Aquaporin-5 / AQP5 antibody

Alternative names for Aquaporin-5 / AQP5 antibody

AQP-5

SwissProt ID

A8W649 (Pig), P47864 (Rat), P55064 (Human), Q9WTY4 (Mouse)

Gene ID

362 (AQP5), 11830 (Aqp5), 25241

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Sh (Sheep), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Aquaporin-5 / AQP5 antibody

Water channel proteins, known as aquaporins, are transmembrane proteins that mediate osmotic water permeability. The discovery of aquaporin (AQP) has made a great impact on life sciences. AQPs are a family of homologous water channels widely distributed in plants, unicellular organisms, invertebrates, and vertebrates. Aquaporins are selective water/glycerol channels involved in the maintenance of volume homeostasis and ionic/osmotic balance. These water channels also enhance cellular tolerance against rapid freezing, which suggest that they might have some ecological relevance also. Early work of Nobel Prize winner, Peter Agre and his group first clone a 269 amino acid protein from RBC and kidney libraries that has a 6 TMD (1). The amino terminal end of the protein was in the membrane and has 2 repeats that are at 180oto each other and are responsible for water selectivity. Now there are atlest 12 isoforms of Aquaporins area cloned.
Acetazolamide can bind to Aquaporin 1 and inhibit the water movement across the plasma membrane. In brain, three main AQPs AQP1, AQP4 and AQP9 are expressed and are implicated in numerous physiological functions. AQP1 has a role in cerebrospinal fluid formation, whereas AQP4 is involved in water homeostasis and extracellular osmotic pressure in brain parenchyma. AQP4 seems also to have an important function in oedema formation after brain trauma or brain ischemia. AQP9 is implicated in brain energy metabolism (2). AQP1 and 4 are also implicated in water balance in retina and other eye components. Studies also suggest that AQP1 may be responsible for the high vascular permeability and interstitial fluid pressure in tumors of the brain, colon, breast and pancreas. AQP1 may also play a role in tumor angiogenesis and in the development of effusions or edema fluid.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Aquaporin-5 / AQP5 antibody

  Anti-AQP5 Rabbit Polyclonal Antibody  
Predicted cell location: Cell membrane, Cytoplasm . Positive control: Human ovarian cancer tissue. Recommended dilution: 1/20-100  The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using AQP5 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aquaporin-5 / AQP5 antibody

  Anti-AQP5 Rabbit Polyclonal Antibody  
Predicted cell location: Cell membrane, Cytoplasm . Positive control: Human esophagus cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using AQP5 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aquaporin-5 / AQP5 antibody

  Rabbit polyclonal Anti-Aquaporin 5  
Western blot analysis of mouse salivary gland (1 and 3) and rat lung (2 and 4): 1, 2. Anti-Aquaporin 5 antibody , (1:200). 3, 4. Anti-Aquaporin 5 antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Aquaporin-5 / AQP5 antibody

  Rabbit Polyclonal Anti-AQP5 Antibody  
Host: Rabbit; Target Name: AQP5; Sample Tissue: COLO205 Whole cell lysates; Antibody Dilution: 1.0 ug/ml. AQP5 is supported by BioGPS gene expression data to be expressed in COLO205 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

Aquaporin-5 / AQP5 antibody

Immunohistochemistry analysis of AQP5 Antibody (Cat.-No AP20601PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Aquaporin-5 / AQP5 (C-term) antibody

AQP5 Polyclonal Antibody Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Aquaporin-5 / AQP5 (C-term) antibody

AQP5 Antibody (C-term) (Cat. #AP50221PU-N) western blot analysis in NCI-H292 cell line lysates (35µg/lane).This demonstrates the AQP5 antibody detected the AQP5 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

AQP5 - human gene knockout kit via CRISPR

AQP5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

AQP5 - human gene knockout kit via CRISPR

AQP5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

AQP5 - human gene knockout kit via CRISPR

AQP5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

AQP5 - human gene knockout kit via CRISPR

AQP5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aqp5 - mouse gene knockout kit via CRISPR

Aqp5 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Aqp5 - mouse gene knockout kit via CRISPR

Aqp5 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aqp5 - mouse gene knockout kit via CRISPR

Aqp5 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aqp5 - mouse gene knockout kit via CRISPR

Aqp5 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

AQP5 overexpression lysate

AQP5 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, AQP5 (mGFP-tagged) - Human aquaporin 5 (AQP5), 200 uL, >10^7 TU/mL

Lenti ORF particles, AQP5 (mGFP-tagged) - Human aquaporin 5 (AQP5), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, AQP5 (Myc-DDK tagged) - Human aquaporin 5 (AQP5) , 200 uL, >10^7 TU/mL

Lenti ORF particles, AQP5 (Myc-DDK tagged) - Human aquaporin 5 (AQP5) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Aqp5 (GFP-tagged) - Mouse aquaporin 5 (Aqp5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Aqp5 (GFP-tagged) - Mouse aquaporin 5 (Aqp5), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Aqp5 (Myc-DDK-tagged) - Mouse aquaporin 5 (Aqp5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Aqp5 (Myc-DDK-tagged) - Mouse aquaporin 5 (Aqp5), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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