ARAP1 / CENTD2 antibody

Principal name

ARAP1 / CENTD2 antibody

Alternative names for ARAP1 / CENTD2 antibody

KIAA0782, Centaurin-delta-2, Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein 1

SwissProt ID

Q4LDD4 (Mouse), Q96P48 (Human)

Gene ID

116985 (ARAP1)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of ARAP1 / CENTD2 antibody

The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. The RHO-GAP activity may mediate cell rounding and loss of stress fibers. At least three transcript variants encoding different isoforms have been found for this gene, but the full-length natures of all variants have not been determined.

General readings

1. Miura K, Jacques KM, Stauffer S, Kubosaki A, Zhu K, Hirsch DS, Resau J, Zheng Y,
Randazzo PA: ARAP1: a point of convergence for Arf and Rho signaling. Mol Cell. 2002
Jan;9(1):109-19.
2. Guo DF, Chenier I, Tardif V, Orlov SN, Inagami T: Type 1 angiotensin II
receptor-associated protein ARAP1 binds and recycles the receptor to the plasma
membrane. Biochem Biophys Res Commun. 2003 Oct 31;310(4):1254-65.
3. Simova S, Klima M, Cermak L, Sourkova V, Andera L: Arf and Rho GAP adapter protein
ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane.
Apoptosis. 2008 Mar;13(3):423-36.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ARAP1 / CENTD2 antibody

Sample (30 ug of whole cell lysate). A: H1299. 5% SDS PAGE. TA308584 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ARAP1 / CENTD2 antibody

Colocalization of ARAP1 with DR4 at the plasma membrane and in early endosomes. ARAP1-transfected NCTC cells were treated with TRAIL for 0´, 30´ or 60´ and fixed with methanol. DR4 was detected by rabbit polyclonal (red) and ARAP1 with ARAP1-2 mouse monoclonal antibody (green). Arrowheads show ARAP1-DR4 colocalization at the plasma membrane and intracellular membranes, whereas arrows show their colocalization in early endosomes. Mouse IgG1 ARAP1-2 Aff - Purified Hu ICC/IF, IP, WB
0.1 mg / €260.00
  Acris Antibodies GmbH

ARAP1 / CENTD2 antibody

Western Blot analysis of ARAP1 expression in transfected 293T cell line (H00116985-T01) by ARAP1 MaxPab polyclonal antibody.

Lane 1: CENTD2 transfected lysate(132.55 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

ARAP1 / CENTD2 antibody

ARAP1 / CENTD2 Mouse IgG1 ARAP1-2 Purified Hu ICC/IF, IP, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

ARAP1 / CENTD2 antibody

ARAP1 / CENTD2 Goat Ms E
0.1 mg / €400.00
  Abnova Taiwan Corp.

ARAP1 / CENTD2 antibody

ARAP1 / CENTD2 Rabbit Hu E, P
50 µg / €480.00
  Novus Biologicals Inc.

ARAP1 / CENTD2 antibody

Western Blot and Immunoprecipitation: CENTD2/ARAP1 Antibody [NB100-68223] - Detection of Human CENTD2/ARAP1 on HeLa whole cell lysate using NB100-68223.  CENTD2/ARAP1 was also immunoprecipitated by another rabbit anti-CENTD2/ARAP1 antibody. Rabbit IgG Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

ARAP1 / CENTD2 antibody

Immunocytochemistry:ARAP1 Antibody (ARAP1-2) [NB110-68801]- Colocalization of ARAP1 with DR4 at the plasma membrane and in early endosomes. ARAP1-transfected NCTC cells were treated with TRAIL for 0´, 30´ or 60´ and fixed with methanol. DR4 was detected by rabbit polyclonal (red) and ARAP1 with ARAP1-2 mouse monoclonal antibody (green). Arrowheads show ARAP1-DR4 colocalization at the plasma membrane and intracellular membranes, whereas arrows show their colocalization in early endosomes. Mouse IgG1 ARAP1-2 Purified Hu ICC/IF, IP, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ARAP1 / CENTD2

ARAP1 / CENTD2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

ARAP1 / CENTD2

ARAP1 / CENTD2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

ARAP1 / CENTD2

ARAP1 / CENTD2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ARAP1 / CENTD2

ARAP1 / CENTD2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ARAP1 overexpression lysate

ARAP1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

CENTD2 293T Cell Transient Overexpression Lysate(Denatured)

CENTD2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

14 Item(s)

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