ARC / ARG3.1 antibody

Principal name

ARC / ARG3.1 antibody

Alternative names for ARC / ARG3.1 antibody

KIAA0278, Activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein homolog

SwissProt ID

Q63053 (Rat), Q7LC44 (Human), Q8AWC3 (Chick), Q9WV31 (Mouse)

Gene ID

23237 (ARC), 11838 (Arc), 54323

Available reactivities

Hu (Human), Ms (Mouse), Chk (Chicken), Rt (Rat), Bov (Bovine), GP (Guinea Pig), Gt (Goat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of ARC / ARG3.1 antibody

Growth factor stimulation has been shown to induce the expression of immediate early genes in non-neuronal cells, which encode a variety of molecules that are potentially involved in long-term cellular responses. Similar responses induced by neurotransmitter stimulation have also been seen in neuronal cells and evidence suggests that protein synthesis is required for long-term synaptic plasticity. Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activitydependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to co-localize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.

General readings

Foo,R.S., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (52), 20826-20831

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ARC / ARG3.1 antibody

  Rabbit Polyclonal Anti-ARC Antibody  
WB Suggested Anti-ARC Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, GP, Gt, Hu, Ms, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

ARC / ARG3.1 antibody

  Rabbit Polyclonal Anti-ARC Antibody  
WB Suggested Anti-ARC Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, GP, Gt, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ARC / ARG3.1 antibody

  Rabbit Polyclonal Anti-ARC Antibody  
Host: Rabbit; Target Name: ARC; Sample Tissue: Ovary Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified GP, Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

ARC / ARG3.1 antibody

  Rabbit Polyclonal Anti-ARC Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Mouse brain tissue, Primary antibody: (ARC Antibody) at dilution 1/597, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ARC / ARG3.1 antibody

Immunohistochemistry (IHC) analysis of ARC / ARG3.1 antibody (Cat.-No AP06016PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ARC - human gene knockout kit via CRISPR

ARC - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ARC - human gene knockout kit via CRISPR

ARC - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ARC - human gene knockout kit via CRISPR

ARC - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ARC - human gene knockout kit via CRISPR

ARC - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Arc - mouse gene knockout kit via CRISPR

Arc - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Arc - mouse gene knockout kit via CRISPR

Arc - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Arc - mouse gene knockout kit via CRISPR

Arc - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Arc - mouse gene knockout kit via CRISPR

Arc - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ARC / ARG3.1

  Recombinant protein of human activity-regulated cytoskeleton-associated protein (ARC)  
ARC / ARG3.1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ARC / ARG3.1 (1-396, His-tag)

ARC / ARG3.1 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €730.00
  Acris Antibodies GmbH

ARC / ARG3.1 (1-396, His-tag)

ARC / ARG3.1 Human Purified > 90 % by SDS - PAGE E. coli
10 µg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

ARC overexpression lysate

ARC overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ARC (mGFP-tagged)-Human activity-regulated cytoskeleton-associated protein (ARC), 200 uL, >10^7 TU/mL

Lenti ORF particles, ARC (mGFP-tagged)-Human activity-regulated cytoskeleton-associated protein (ARC), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ARC (Myc-DDK-tagged)-Human activity-regulated cytoskeleton-associated protein (ARC), 200 uL, >10^7 TU/mL

Lenti ORF particles, ARC (Myc-DDK-tagged)-Human activity-regulated cytoskeleton-associated protein (ARC), 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Arc (GFP-tagged ORF) - Rat activity-regulated cytoskeleton-associated protein (Arc), 200 uL, >10^7 TU/mL

Lenti ORF particles, Arc (GFP-tagged ORF) - Rat activity-regulated cytoskeleton-associated protein (Arc), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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