ARFGEF2 antibody

Principal name

ARFGEF2 antibody

Alternative names for ARFGEF2 antibody

ARFGEP2, BIG2, Brefeldin A-inhibited GEP2, Brefeldin A-inhibited guanine nucleotide-exchange protein 2

SwissProt ID

Q9Y6D5 (Human)

Gene ID

10564 (ARFGEF2)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human)

Available hosts

Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of ARFGEF2 antibody

Guanine nucleotide-exchange proteins (GEPs) accelerate replacement of bound GDP with GTP and thereby activate ADP-ribosylation factors (ARFs), a family of guanine nucleotide-binding proteins that play an important role in intracellular vesicular trafficking. GEPs comprise two major families, large GEPs that are inhibited by brefeldin A (BFA), a protein that effects golgi structure, and a group of smaller GEPs that are insenstive to BFA. Two genes for GEPs found on human chromosomes 8 and 20 encode BFA sensitive GEPs of approximately 200 kDa, designated BIG1 and BIG2. Both GEPS contain a sec7 domain that is responsible for their brefeldin inhibition and also their catalytic activity. In vivo, BIG1 and BIG2 exist in macromolecular complexes that move between the golgi membranes and cytosol. BIG2 associates with PKA regulatory subunits, implying that BIG2 may act as an A kinase-anchoring protein (AKAP) that could coordinate the cAMP and ARF regulatory pathways.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ARFGEF2 antibody

Western blot analysis of extracts from A549 cells, using ARFGEF2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ARFGEF2 antibody

Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only. Rabbit IgG Purified Hu E, ICC/IF, P
50 µg / €325.00
  OriGene Technologies, Inc.

ARFGEF2 antibody

Immunohistochemistry (IHC) analyzes of BIG2 antibody (Cat.-No.: AP01387PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

ARFGEF2 antibody

Immunofluorescence analysis of A549 cells, using ARFGEF2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

ARFGEF2 antibody

Immunofluorescence analysis of A549 cells, using ARFGEF2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

ARFGEF2 antibody

ELISA: ARFGEF2 Antibody [35480002] Rabbit Hu E, P
50 µg / €400.00
  Novus Biologicals Inc.

ARFGEF2 antibody

Immunohistochemistry: BIG2 Antibody [NBP1-00725] - Immunohistochemistry (IHC) analyzes of BIG2 (L1527) antibody in paraffin-embedded human colon carcinoma tissue Rabbit Aff - Purified Ms, Rt ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

ARFGEF2 antibody

ARFGEF2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

ARFGEF2 antibody

ARFGEF2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €290.00
  Novus Biologicals Inc.

9 Item(s)

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