ARHGAP26 / OPHN1L antibody

Principal name

ARHGAP26 / OPHN1L antibody

Alternative names for ARHGAP26 / OPHN1L antibody

Oligophrenin-1-like protein, GRAF, KIAA0621, Rho GTPase-activating protein 26, Rho-type GTPase-activating protein 26, GTPase regulator associated with focal adhesion kinase

SwissProt ID

Q5ZMW5 (Chick), Q6ZQ82 (Mouse), Q9UNA1 (Human)

Gene ID

23092 (ARHGAP26), 71302 (Arhgap26)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of ARHGAP26 / OPHN1L antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

General readings

1. Borkhardt A, Bojesen S, Haas OA, Fuchs U, Bartelheimer D, Loncarevic IF, Bohle RM, Harbott J, Repp R, Jaeger U, Viehmann S, Henn T, Korth P, Scharr D, Lampert F.
The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q.
Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9168-73.
PMID: 10908648

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ARHGAP26 / OPHN1L (C-term) antibody

  Goat Polyclonal Antibody against ARHGAP26  
TA302899 (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide.  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ARHGAP26 / OPHN1L (Center) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ARHGAP26 - human gene knockout kit via CRISPR

ARHGAP26 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ARHGAP26 - human gene knockout kit via CRISPR

ARHGAP26 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ARHGAP26 - human gene knockout kit via CRISPR

ARHGAP26 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ARHGAP26 - human gene knockout kit via CRISPR

ARHGAP26 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Arhgap26 - mouse gene knockout kit via CRISPR

Arhgap26 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Arhgap26 - mouse gene knockout kit via CRISPR

Arhgap26 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Arhgap26 - mouse gene knockout kit via CRISPR

Arhgap26 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Arhgap26 - mouse gene knockout kit via CRISPR

Arhgap26 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ARHGAP26 / OPHN1L (transcript variant 1)

  Recombinant protein of human Rho GTPase activating protein 26 (ARHGAP26), transcript variant 1  
ARHGAP26 / OPHN1L Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ARHGAP26 overexpression lysate

ARHGAP26 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ARHGAP26 (mGFP-tagged)-Human Rho GTPase activating protein 26 (ARHGAP26), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ARHGAP26 (mGFP-tagged)-Human Rho GTPase activating protein 26 (ARHGAP26), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ARHGAP26 (Myc-DDK-tagged)-Human Rho GTPase activating protein 26 (ARHGAP26), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ARHGAP26 (Myc-DDK-tagged)-Human Rho GTPase activating protein 26 (ARHGAP26), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Arhgap26 (GFP-tagged) - Mouse Rho GTPase activating protein 26 (Arhgap26), 200 uL, >10^7 TU/mL

Lenti ORF particles, Arhgap26 (GFP-tagged) - Mouse Rho GTPase activating protein 26 (Arhgap26), 200 uL, >10^7 TU/mL  
200 µl / €1,540.00
  OriGene Technologies, Inc.

Lenti ORF particles, Arhgap26 (Myc-DDK-tagged) - Mouse Rho GTPase activating protein 26 (Arhgap26), 200 uL, >10^7 TU/mL

Lenti ORF particles, Arhgap26 (Myc-DDK-tagged) - Mouse Rho GTPase activating protein 26 (Arhgap26), 200 uL, >10^7 TU/mL  
200 µl / €1,380.00
  OriGene Technologies, Inc.

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