ARHGEF17 / TEM4 antibody

Principal name

ARHGEF17 / TEM4 antibody

Alternative names for ARHGEF17 / TEM4 antibody

KIAA0337, p164-RhoGEF, p164RhoGEF, Tumor endothelial marker 4, 164 kDa Rho-specific guanine-nucleotide exchange factor, Rho guanine nucleotide exchange factor 17

SwissProt ID

Q80U35 (Mouse), Q96PE2 (Human)

Gene ID

9828 (ARHGEF17), 207212 (Arhgef17)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts


Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C)

Background of ARHGEF17 / TEM4 antibody

TEM4 (Tumor endothelial marker 4) is a Rho-specific GEF (guanine-nucleotide exchange factor) with novel structural and regulatory properties and predominant expression in the heart. Rho GTPases, which are activated by specific GEFs, play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful as a target, therapeutically.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ARHGEF17 / TEM4 antibody

Human Kidney (formalin-fixed, paraffin-embedded) stained with ARHGEF17 antibody AP22665PU-N at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ARHGEF17 / TEM4 (Center) antibody

Western blot analysis of TEM4 in Jurkat Cell lysate with TEM4 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ARHGEF17 / TEM4 Control Peptide

50 µg / €160.00
  Acris Antibodies GmbH

ARHGEF17 / TEM4 antibody

Immunohistochemistry of ARHGEF17 in human spleen tissue with ARHGEF17 polyclonal antibody ( Cat # PAB13013 ) at 2.5 µg/ml. Rabbit Hu P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

ARHGEF17 / TEM4 antibody

ARHGEF17 / TEM4 Rabbit IgG Aff - Purified Ms WB
50 µg / €680.00
  Funakoshi Co., Ltd.

5 Item(s)

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