ARHGEF4 antibody

Principal name

ARHGEF4 antibody

Alternative names for ARHGEF4 antibody

KIAA1112, ASEF, Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor

SwissProt ID

Q7TNR9 (Mouse), Q9NR80 (Human)

Gene ID

50649 (ARHGEF4)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of ARHGEF4 antibody

ARHGEF4 (Rho guanine nucleotide exchange factor 4), also known as ASEF 1 (adenomatous polyposis coli – stimulated guanine nucleotide exchange factor 1) is an approximately 80 kDa cytoplasmic protein important for growth factor-mediated regulation of cell morphology and migration. Besides N-terminal adenomatous polyposis coli (APC)-binding region (ABR) it contains Dbl homology (DH), Pleckstrin homology (PH) and SH3 domains. The SH3 domain inhibits GEF activity of ARHGEF4 by intramolecular interaction with the DH domain, whereas binding of APC stimulates the GEF activity. Activated ARHGEF4 stimulates the small GTPase Cdc42, which leads to decreased cell-cell adherence and enhanced cell migration.

General readings

Thiesen S, Kubart S, Ropers HH, Nothwang HG.
Isolation of two novel human RhoGEFs, ARHGEF3 and ARHGEF4, in 3p13-21 and 2q22.
Biochem Biophys Res Commun. 2000 Jun 24;273(1):364-9.
PMID: 10873612

13 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ARHGEF4 (N-term) antibody

TA302416 (2µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ARHGEF4 (143-271) antibody

Western blotting analysis of ARHGEF4 in HEK293 cells (A) and HEK293-ARHGEF4 transfectants (B) using mouse monoclonal anti-ARHGEF4 (clone ARHGEF-08). Mouse IgG1 ARHGEF-08 Aff - Purified Hu F, WB
0.1 mg / €230.00
  Acris Antibodies GmbH

ARHGEF4 (143-271) antibody

Western blot analysis of ARHGEF4 in HEK293 cells (A) and HEK293-ARHGEF4 transfectants (B) using mouse monoclonal anti-ARHGEF4 (clone ARHGEF-08). Mouse IgG1 ARHGEF-08 PE Hu F
0.1 mg / €290.00
  Acris Antibodies GmbH

ARHGEF4 antibody

ARHGEF4 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

ARHGEF4 antibody

ARHGEF4 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

ARHGEF4 antibody

ARHGEF4 polyclonal antibody ( Cat # PAB6484 ) staining ( 2 µg/ml ) of human brain lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

ARHGEF4 antibody

Western blot: ARHGEF4 Antibody [NB100-1316]-HEK293 overexpressing ARHGEF4 and probed with EB06107 (mock transfection in first lane). Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

ARHGEF4 antibody

Immunohistochemistry-Paraffin: ARHGEF4 Antibody [NBP1-88857] Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ARHGEF4

ARHGEF4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ARHGEF4

ARHGEF4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

ARHGEF4

ARHGEF4 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

ARHGEF4

ARHGEF4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ARHGEF4

ARHGEF4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

13 Item(s)

per page
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