ARMS / KIDINS220 antibody

Principal name

ARMS / KIDINS220 antibody

Alternative names for ARMS / KIDINS220 antibody

KIAA1250, Kinase D-interacting substrate of 220 kDa, Ankyrin repeat-rich membrane spanning protein

SwissProt ID

Q9ULH0 (Human)

Gene ID

57498 (KIDINS220)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Dot blot (Dot), Flow Cytometry (F)

Background of ARMS / KIDINS220 antibody

KIDINS220 promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin-and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.

General readings

Wu, Z., et al. J. Biol. Chem. 283(42):28198-28215(2008)
Sniderhan, L.F., et al. Mol. Cell. Neurosci. 38(3):404-416(2008)
Li, J., et al. J. Biol. Chem. 283(5):2614-2621(2008)
Liao, Y.H., et al. Cancer Res. 67(24):11547-11556(2007)
Bracale, A., et al. Mol. Biol. Cell 18(1):142-152(2007)

4 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ARMS / KIDINS220 antibody

Sample(30 ug whole cell lysate). A:H1299. B:Raji . 5% SDS PAGE. TA308619 diluted at 1:1000 Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ARMS / KIDINS220 (C-term) antibody

Western blot analysis of ARMS / KIDINS220 Antibody (C-term) Cat.-No AP52362PU-N in K562 cell line lysates (35ug/lane). This demonstrates the KIDINS220 antibody detected the KIDINS220 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ARMS / KIDINS220 antibody

ARMS / KIDINS220 Rabbit Purified Hu, Ms WB
0.1 ml / €310.00
  Neuromics Antibodies

ARMS / KIDINS220 pSer919 antibody

ARMS / KIDINS220 Rabbit Purified Hu, Ms WB
0.1 ml / €310.00
  Neuromics Antibodies

4 Item(s)

per page
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