ARNTL / BMAL1 antibody

Principal name

ARNTL / BMAL1 antibody

Alternative names for ARNTL / BMAL1 antibody

BHLHE5, MOP3, PASD3, bHLHe5, bHLH-PAS protein JAP3, Aryl hydrocarbon receptor nuclear translocator-like protein 1, Basic-helix-loop-helix-PAS protein MOP3, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5, Member of PAS protein 3, PAS domain-containing protein 3

SwissProt ID

A0MLS5 (Horse), O00327 (Human), O88529 (Mesau), Q9EPW1 (Rat), Q9I8T7 (Chick), Q9WTL8 (Mouse)

Gene ID

11865 (Arntl), 406 (ARNTL)

Available reactivities

GP (Guinea Pig), Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Can (Canine), Por (Porcine), Chk (Chicken), Eq (Equine), Rb (Rabbit), Sh (Sheep)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), ChIP assay (ChIP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Immunoprecipitation (IP), Flow Cytometry (F), Frozen Sections (C)

Background of ARNTL / BMAL1 antibody

Circadian rhythmicity is a basic property of phylogenetically diverse organisms which range from animals and plants, to fungi. Regulation of endogenous biological clocks is regulated at the genetic level by a protein-mediated, autoregulatory feed-back loop. In mammals, several genes that encode members of the basic helix-loop helix (bHLH) PAS (PER-ARNT-SIM) transcription factor family have been shown to play a significant role in regulating circadian oscillations. Transactivation of CLOCK-induced genes is mediated via an E box enhancer (CACGTG) found upstream of target genes. CLOCK-ARNT3 heterodimers bind to E box regulatory elements and stimulate gene transcription. CLOCK has been shown to transactivate the mammalian homolog of Drosophila per. PER, in concert with the product of the mammalian timeless gene (TIM), negatively regulates its own transcription by blocking the activity of the CLOCK-BMAL1 transactivation complex.

General readings

1. Fuller PM, Lu J, Saper CB. Differential rescue of light- and food-entrainable circadian rhythms.
Science 2008 May 320 (5879): 1074-7. PMID: 18497298

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ARNTL / BMAL1 antibody

Immunohistochemical staining of paraffin-embedded lung tissue within the normal limits using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501174, Dilution 1:50) Mouse IgG1 OTI1C11 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ARNTL / BMAL1 antibody

Figure from citation: Immunohistochemistry of ARNTL(BMAL1) protein level by using anti-ARNTL antibody in coronal sections of the main olfactory bulb (MOB) portion of 7-day-old rabbits. Dilution: 1:200 View Citation Mouse IgG1 OTI1D1 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ARNTL / BMAL1 antibody

Western Blot: BMAL1 Antibody- Analysis of BMAL1 in A) MCF7, B) NIH/3T3, C) PC12. Rabbit IgG Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ARNTL / BMAL1 antibody

Immunohistochemical staining of paraffin-embedded Human lung tissue within the normal limits using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA501227) Mouse IgG1 OTI1H6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ARNTL / BMAL1 antibody

Anti-ARNTL mouse monoclonal antibody (TA501277) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARNTL(RC207870). Mouse IgG1 OTI3G9 Purified Can, Hu, Rt F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

ARNTL / BMAL1 antibody

Western Blot: BMAL1 Antibody TA301766 - Detection of BMAL in 3T3/L1 lysates. Rabbit IgG Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

ARNTL / BMAL1 (both Isoforms) antibody

TA305628 (0.3ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ARNTL / BMAL1 antibody

WB Suggested Anti-ARNTL Antibody Titration: 5.0 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ARNTL / BMAL1 antibody

WB Suggested Anti-ARNTL Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: NIH/3T3 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ARNTL / BMAL1 antibody

Host: Rabbit; Target Name: Arntl; Sample Tissue: Mouse Stomach lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

ARNTL / BMAL1 antibody

Immunohistochemical analysis of paraffin-embedded human Spleen tissues using anti-ARNTL mouse mAb Mouse IgG1 1C5 Ascites Hu E, P, WB
0.1 ml / €360.00
  Acris Antibodies GmbH

ARNTL / BMAL1 (569-573) antibody

Western blot analysis of extracts from mouse brain tissue using BMAL1 antibody AP26055PU-N. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Acris Antibodies GmbH

ARNTL / BMAL1 (569-573) antibody

Western blot analysis of extracts from mouse brain tissue using BMAL1 antibody AP26055PU-N. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €230.00
  Acris Antibodies GmbH

ARNTL / BMAL1 antibody

Western Blot analysis of ARNTL expression in transfected 293T cell line (H00000406-T01) by ARNTL MaxPab polyclonal antibody.

Lane 1: ARNTL transfected lysate(68.75 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

ARNTL / BMAL1 antibody

ARNTL polyclonal antibody ( Cat # PAB11615 ) ( 0.3 µg/ml ) staining of human brain ( cerebellum ) lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

ARNTL / BMAL1 antibody

Lanes 1-3 contained ARNTL immunoprecipitated DNA ( 60, 40 & 20 µl of antisera respectively ). ARNTL polyclonal antibody ( Cat # PAB12484 ) was used. Rabbit Hu ChIP, IP, WB
0.4 ml / €470.00
  Abnova Taiwan Corp.

ARNTL / BMAL1 antibody

Human Skin; ARNTL antibody - N-terminal region (ARP32002_T100) in Human Skin cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

ARNTL / BMAL1 antibody

Mouse NIH-3T3; WB Suggested Anti-ARNTL Antibody Titration: 1.25ug/ml. ELISA Titer: 1:312500. Positive Control: NIH/3T3 cell lysate; ARNTL antibody - N-terminal region (ARP36822_T100) in Mouse NIH-3T3 cells using Western Blot Rabbit IgG Purified Bov, Can, Chk, Hu, Ms, Por, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

ARNTL / BMAL1 antibody

ARNTL / BMAL1 Rabbit Purified Hu ChIP, WB
0.1 ml / €160.00
  Novus Biologicals Inc.

ARNTL / BMAL1 antibody

ARNTL / BMAL1 Rabbit Biotin Hu WB
0.1 ml / €360.00
  Novus Biologicals Inc.

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