Aromatase antibody

Principal name

Aromatase antibody

Alternative names for Aromatase antibody

Cytochrome P450 19A1, CYPXIX, Estrogen synthetase, P450AROM, CYP19A1, ARO1, CYAR, CYP19

SwissProt ID

O46512 (Horse), P11511 (Human), P19098 (Chick), P22443 (Rat), P28649 (Mouse), P46194 (Bovin)

Gene ID

1588 (CYP19A1), 13075 (Cyp19a1)

Available reactivities

Bov (Bovine), Chk (Chicken), Eq (Equine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Sh (Sheep), Bt (Bat), Gt (Goat), Marmoset, Mky (Monkey), Bab (Baboon), Prim (Primate)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Frozen Sections (C), ELISA (detection) (E(detection))

Selected product citations ‐ of SM2222P

1. Colette S, Lousse JC, Defrère S, Curaba M, Heilier JF, Van Langendonckt A, et al. Absence of aromatase protein and mRNA expression in endometriosis. Hum Reprod. 2009 Sep;24(9):2133-41. doi: 10.1093/humrep/dep199. Epub 2009 Jun 2. PubMed PMID: 19493871.
2. Bender RA, Zhou L, Wilkars W, Fester L, Lanowski JS, Paysen D, et al. Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus. Cereb Cortex. 2010 Dec;20(12):2985-95. doi: 10.1093/cercor/bhq047. Epub 2010 Apr 26. PubMed PMID: 20421250.
3. Horling K, Santos AN, Fischer B. The AhR is constitutively activated and affects granulosa cell features in the human cell line KGN. Mol Hum Reprod. 2011 Feb;17(2):104-14. doi: 10.1093/molehr/gaq074. Epub 2010 Sep 7. PubMed PMID: 20823264.
4. Schicht M, Ernst J, Nielitz A, Fester L, Tsokos M, Guddat SS, et al. Articular cartilage chondrocytes express aromatase and use enzymes involved in estrogen metabolism. Arthritis Res Ther. 2014 Apr 11;16(2):R93. doi: 10.1186/ar4539. PubMed PMID: 24725461. 
5. Zhao, Y;Yu, Y;Zhang, Y;He, L;Qiu, L;Zhao, J;Liu, M;Zhang, J. Letrozole regulates actin cytoskeleton polymerization dynamics in a SRC-1 dependent manner in the hippocampus of mice. J. Steroid Biochem. Mol. Biol. 2016. PubMed PMID: 27866972. 
6. Fouquet, B;Santulli, P;Noel, JC;Misrahi, M. Ovarian-like differentiation in eutopic and ectopic endometrioses with aberrant FSH receptor, INSL3 and GATA4/6 expression. BBA Clin 2016, 143-152, 6. PubMed PMID: 27882303.

Background of Aromatase antibody

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. P450 enzymes can be classified, based on their sequence similarities, into distinct subfamilies, which include CYP1A and CYP2A. Other P450 family members include CYP19, also designated aromatase (P450arom), which catalyzes the conversion of C19 steroids to estrogens in various tissues, including placent,a gonads, adipose tissue, skin and brain. CYP19 expression is controlled by hormonally regulated promoters in different tissues and increased aromatase activity is associated with familial gynecomastia. Also, a polymorphic allele of CYP19 (repeat (TTTA)12) is present in a majority of breast cancer patients. P450 cholesterol 7α-hydroxylase, CYP7A1, is the rate limiting enzyme of bile acid synthesis in the liver, and its expression is mediated by the bile acid receptor FXR. CYP27A1 catalyzes vitamin D 25-hydroxylation and is localized to the mitochondria in kidney and liver.

General readings

1. Van Poznak CH, Hayes DF. Aromatase inhibitors for the treatment of breast cancer: is tamoxifen of historical interest only?
J Natl Cancer Inst. 2006 Sep 20;98(18):1261-3. No abstract available.
PMID: 16985239

  1. Quick-Filters:
  2. Cited (1)
  3. Overnight Delivery (3)

Items 1 to 20 of 25 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Aromatase antibody

Immunohistochemical staining of human placenta using Aromatase antibody AP00001PU-N showed staining of trophoblasts (Placental Villi 40X). Rabbit Purified Bov, Chk, Eq, Hu, Ms, Por, Rb, Rt, Sh P, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

Aromatase (376-390) antibody

Western blot analysis of Human placenta extract probed with anti Human Cytochrome P450 Aromatase Antibody Cat.-No SM2222P/PS (Clone H4) followed by F(ab')2 Rabbit anti Mouse IgG-HRP (Cat.-No SP1012HRP). Mouse IgG2a H4 Supernatant Bab, Bov, Bt, Chk, Eq, Gt, Hu, Marmoset, Mky, Ms, Por, Rb, Rt, Sh ICC/IF, P, WB
1 ml / €880.00
  Acris Antibodies GmbH

Aromatase (376-390) antibody

Western blot analysis of Human placenta extract probed with anti Human Cytochrome P450 Aromatase Antibody Cat.-No SM2222P/PS (Clone H4) followed by F(ab')2 Rabbit anti Mouse IgG-HRP (Cat.-No SP1012HRP). Mouse IgG2a H4 Supernatant Bab, Bov, Chk, Eq, Gt, Hu, Marmoset, Mky, Ms, Por, Rb, Rt, Sh ICC/IF, P, WB
0.2 ml / €220.00
  Acris Antibodies GmbH

Aromatase (376-390) antibody

Western blot analysis of Human placenta extract probed with anti Human Cytochrome P450 Aromatase Antibody Cat.-No SM2222P/PS (Clone H4) followed by F(ab')2 Rabbit anti Mouse IgG-HRP (Cat.-No SP1012HRP). Mouse IgG2a H4 Supernatant Bab, Bov, Chk, Eq, Gt, Hu, Marmoset, Ms, Por, Rb, Rt, Sh ICC/IF, P, WB
50 µl / €80.00
  Acris Antibodies GmbH

Aromatase antibody

  Rabbit Polyclonal Antibody against Aromatase  
Detection of aromatasein human fetal temporal lobe lysate. ECL exposure, 1-2 minutes Rabbit IgG Purified Hu, Mky WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aromatase antibody

  Goat Polyclonal Antibody against Aromatase / CYP19A1  
TA302418 (0.1µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Aromatase antibody

  Rabbit polyclonal Cytochrome P450 19A1 antibody  
Western blot analysis of extracts from 293 cells, using Cytochrome P450 19A1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aromatase antibody

  Anti-ARO Rabbit Polyclonal Antibody  
Western blot analysis of Human ovarian cancer tissue using TA321053(CYP19A1 Antibody) at dilution 1/100 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aromatase antibody

  Anti-ARO Rabbit Polyclonal Antibody  
Western blot analysis of Human ovarian cancer tissue using TA321054(CYP19A1 Antibody) at dilution 1/100 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aromatase antibody

  Rabbit anti-CYP19A1 Polyclonal Antibody  
Western blot analysis of extracts of Jurkat cell lines, using CYP19A1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Aromatase (Center) antibody

AP14030PU-N CYP19A1 antibody staining of HL60 cell line lysates by Western blot (35 µg/lane). CYP19A1 (arrow) was detected using the purified antibody at 1/60 dilution. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Aromatase (C-term) antibody

AP14221PU-N CYP19A1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human placenta tissue using peroxidase-conjugate and DAB chromogen. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Aromatase antibody

Immunohistochemistry analysis of CYP19A1 Antibody (Cat.-No.: AP20542PU-N) in Paraffin-Embedded Human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Aromatase (475-486) antibody

Human Placenta (formalin-fixed, paraffin-embedded) stained with CYP19A1 antibody AP22508PU-N at 4 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Hu, Mky, Prim E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Aromatase antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Cytochrome P450 19A1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

Aromatase antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Cytochrome P450 19A1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CYP19A1 - human gene knockout kit via CRISPR

CYP19A1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CYP19A1 - human gene knockout kit via CRISPR

CYP19A1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYP19A1 - human gene knockout kit via CRISPR

CYP19A1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYP19A1 - human gene knockout kit via CRISPR

CYP19A1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Items 1 to 20 of 25 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn