ASAP2 / DDEF2 antibody

Principal name

ASAP2 / DDEF2 antibody

Alternative names for ASAP2 / DDEF2 antibody

PAG3, PAP, KIAA0400, Arf-GAP with SH3 domain ANK repeat and PH domain-containing protein 2, Development and differentiation-enhancing factor 2, Paxillin-associated protein with ARF GAP activity 3, Pyk2 C-terminus-associated protein

SwissProt ID

O43150 (Human), Q7SIG6 (Mouse)

Gene ID

8853 (ASAP2), 211914 (Asap2)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of ASAP2 / DDEF2 antibody

This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ASAP2 / DDEF2 antibody

Host: Rabbit; Target Name: ASAP2; Sample Tissue: MCF7 Whole Cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ASAP2 / DDEF2 antibody

DDEF2 polyclonal antibody (A01), Lot # 060501JCS1 Western Blot analysis of DDEF2 expression in SJCRH30 ( Cat # L027V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

ASAP2 / DDEF2 antibody

Western Blot analysis of ASAP2 expression in transfected 293T cell line (H00008853-T01) by ASAP2 MaxPab polyclonal antibody.

Lane1:DDEF2 transfected lysate(110.66 KDa).
Lane2:Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

ASAP2 / DDEF2 antibody

ASAP2 / DDEF2 Rabbit IgG Aff - Purified Hu, Ms WB
50 µg / €680.00
  Funakoshi Co., Ltd.

ASAP2 / DDEF2 antibody

Western Blot: PAG3 Antibody [NBP1-78214]-Whole cell lysate from HeLa (15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Affinity purified rabbit anti-ASAP2 antibody  used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate.  ASAP2 was also immunoprecipitated by another rabbit anti-ASAP2 antibody which recognizes an upstream epitope. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ASAP2 / DDEF2

ASAP2 / DDEF2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ASAP2 / DDEF2

ASAP2 / DDEF2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

ASAP2 / DDEF2

ASAP2 / DDEF2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ASAP2 / DDEF2

ASAP2 / DDEF2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DDEF2 293T Cell Transient Overexpression Lysate(Denatured)

DDEF2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

ASAP2 overexpression lysate

ASAP2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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