ASB12 antibody

Principal name

ASB12 antibody

Alternative names for ASB12 antibody

Ankyrin repeat and SOCS box protein 12

Gene ID

142689 (ASB12)

Available reactivities

Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts


Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of ASB12 antibody

Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-12 (ankyrin repeat and SOCS box-containing 12) is ag 309 amino acid member of the ASB family that contains one SOCS box domain and five ANK repeats. ASB-12 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins.

General readings

Ross,M.T., (2005) Nature 434 (7031), 325-337

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ASB12 antibody

ASB12 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
  OriGene Technologies, Inc.

ASB12 antibody

ASB12 Rabbit Aff - Purified Can, Chk, Hu, Ms, Rt WB
  AVIVA Systems Biology

ASB12 antibody

ASB12 Rabbit Aff - Purified Hu, Ms, Rt WB
  Novus Biologicals Inc.

3 Item(s)

per page
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