Ataxin-1 antibody

Principal name

Ataxin-1 antibody

Alternative names for Ataxin-1 antibody

Ataxin 1, ATXN1, ATX1, SCA1, Spinocerebellar ataxia type 1 protein

SwissProt ID

P54253 (Human), P54254 (Mouse), Q63540 (Rat)

Gene ID

6310 (ATXN1), 20238 (Atxn1)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Por (Porcine), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C)

Background of Ataxin-1 antibody

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Ataxin-1 antibody

Transfected cell immunoblot: COS cells transiently transfected with Ataxin-1 and Kv2.1 plasmids and probed with N76/8 TC supe. Mouse IgG2b N76/8 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

Transfected cell immunoblot: COS cells transiently transfected with Ataxin-1 and Kv2.1 plasmids and probed with N76/8 TC supe. Mouse IgG2b N76/8 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues (left) and lung cancer tissues (right) using ATXN1 antibody Cat.-No AM06558SU-N with DAB staining. Mouse IgG1 2F5 Ascites Hu E, F, ICC/IF, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

Ataxin-1 antibody

Western blot analysis of Ataxin 1 expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Ataxin-1 antibody

Western blot analysis of extracts of various cell lines, using ATXN1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ataxin-1 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N65/37 Supernatant Hu, Ms, Rt ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

adult mouse brain immunoblot: extracts of cerebella from Ataxin-1 KO and WT mice and probed with N76/3 TC supe. Image courtesy of Drs. Paymaan Jafad-Nejad and Huda Zoghbi, Baylor College of Medicine. Mouse IgG1 N76/3 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N65/37 Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

adult mouse brain immunoblot: extracts of cerebella from Ataxin-1 KO and WT mice and probed with N76/3 TC supe. Image courtesy of Drs. Paymaan Jafad-Nejad and Huda Zoghbi, Baylor College of Medicine. Mouse IgG1 N76/3 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

Western blot analysis of anti-ATXN1 Antibody (S776) (Cat.#AP12458PU-N) in CEM cell line lysates (35ug/lane). ATXN1 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Ataxin-1 (C-term) antibody

Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms E, ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

Ataxin-1 antibody

Ataxin-1 Mouse IgG2b 4C5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Ataxin-1 pSer776 antibody

Immunofluorescence analysis of NIH-3T3 cells, using Ataxin 1 (Phospho-Ser776) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

Ataxin-1 pSer776 antibody

Immunofluorescence analysis of NIH-3T3 cells, using Ataxin 1 (Phospho-Ser776) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

Ataxin-1 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Ataxin 1 (Ab-776) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

Ataxin-1 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Ataxin 1 (Ab-776) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

Ataxin-1 antibody

Ataxin-1 Rabbit IgG Aff - Purified Hu WB
0.1 mg / €290.00
  Boster Immunoleader

Ataxin-1 pSer775 antibody

Immunohistochemical analysis of Ataxin 1 (pS775) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
30 µl / €210.00
  Cohesion Biosciences Ltd.

Ataxin-1 pSer775 antibody

Immunohistochemical analysis of Ataxin 1 (pS775) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €330.00
  Cohesion Biosciences Ltd.

Ataxin-1 pSer775 antibody

Immunohistochemical analysis of Ataxin 1 (pS775) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.2 ml / €530.00
  Cohesion Biosciences Ltd.

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